Nagai Y - Search Results

1

Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.

Ishiguro T, Sato N, Ueyama M, Fujikake N, Sellier C, Kanegami A, Tokuda E, Zamiri B, Gall-Duncan T, Mirceta M, Furukawa Y, Yokota T, Wada K, Taylor JP, Pearson CE, Charlet-Berguerand N, Mizusawa H, Nagai Y, Ishikawa K. Ishiguro T, et al. Among authors: nagai y. Neuron. 2017 Apr 5;94(1):108-124.e7. doi: 10.1016/j.neuron.2017.02.046. Epub 2017 Mar 23. Neuron. 2017. PMID: 28343865 Free PMC article.

2

Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila.

Nagai Y, Fujikake N, Ohno K, Higashiyama H, Popiel HA, Rahadian J, Yamaguchi M, Strittmatter WJ, Burke JR, Toda T. Nagai Y, et al. Hum Mol Genet. 2003 Jun 1;12(11):1253-9. doi: 10.1093/hmg/ddg144. Hum Mol Genet. 2003. PMID: 12761040

3

Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity.

Popiel HA, Nagai Y, Onodera O, Inui T, Fujikake N, Urade Y, Strittmatter WJ, Burke JR, Ichikawa A, Toda T. Popiel HA, et al. Among authors: nagai y. Biochem Biophys Res Commun. 2004 May 14;317(4):1200-6. doi: 10.1016/j.bbrc.2004.03.161. Biochem Biophys Res Commun. 2004. PMID: 15094397

4

Humanin attenuates apoptosis induced by DRPLA proteins with expanded polyglutamine stretches.

Kariya S, Hirano M, Nagai Y, Furiya Y, Fujikake N, Toda T, Ueno S. Kariya S, et al. Among authors: nagai y. J Mol Neurosci. 2005;25(2):165-9. doi: 10.1385/JMN:25:2:165. J Mol Neurosci. 2005. PMID: 15784964

5

Alternative splicing regulates the transcriptional activity of Drosophila heat shock transcription factor in response to heat/cold stress.

Fujikake N, Nagai Y, Popiel HA, Kano H, Yamaguchi M, Toda T. Fujikake N, et al. Among authors: nagai y. FEBS Lett. 2005 Jul 4;579(17):3842-8. doi: 10.1016/j.febslet.2005.05.074. FEBS Lett. 2005. PMID: 15978579 Free article.

6

Cytoprotective effect of novel histone deacetylase inhibitors against polyglutamine toxicity.

Kariya S, Hirano M, Uesato S, Nagai Y, Nagaoka Y, Furiya Y, Asai H, Fujikake N, Toda T, Ueno S. Kariya S, et al. Among authors: nagai y. Neurosci Lett. 2006 Jan 16;392(3):213-5. doi: 10.1016/j.neulet.2005.09.019. Epub 2005 Sep 30. Neurosci Lett. 2006. PMID: 16199124

7

Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan.

Xiong H, Kobayashi K, Tachikawa M, Manya H, Takeda S, Chiyonobu T, Fujikake N, Wang F, Nishimoto A, Morris GE, Nagai Y, Kanagawa M, Endo T, Toda T. Xiong H, et al. Among authors: nagai y. Biochem Biophys Res Commun. 2006 Dec 1;350(4):935-41. doi: 10.1016/j.bbrc.2006.09.129. Epub 2006 Oct 2. Biochem Biophys Res Commun. 2006. PMID: 17034757

8

Protein transduction domain-mediated delivery of QBP1 suppresses polyglutamine-induced neurodegeneration in vivo.

Popiel HA, Nagai Y, Fujikake N, Toda T. Popiel HA, et al. Among authors: nagai y. Mol Ther. 2007 Feb;15(2):303-9. doi: 10.1038/sj.mt.6300045. Mol Ther. 2007. PMID: 17235308 Free article.

9

A toxic monomeric conformer of the polyglutamine protein.

Nagai Y, Inui T, Popiel HA, Fujikake N, Hasegawa K, Urade Y, Goto Y, Naiki H, Toda T. Nagai Y, et al. Nat Struct Mol Biol. 2007 Apr;14(4):332-40. doi: 10.1038/nsmb1215. Epub 2007 Mar 18. Nat Struct Mol Biol. 2007. PMID: 17369839

10

[Therapeutic strategies for the polyglutamine diseases].

Nagai Y, Popiel HA, Fujikake N, Toda T. Nagai Y, et al. Brain Nerve. 2007 Apr;59(4):393-404. Brain Nerve. 2007. PMID: 17447526 Review. Japanese.

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