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A functional variant in NEPH3 gene confers high risk of renal failure in primary hematuric glomerulopathies. Evidence for predisposition to microalbuminuria in the general population.
Voskarides K, Stefanou C, Pieri M, Demosthenous P, Felekkis K, Arsali M, Athanasiou Y, Xydakis D, Stylianou K, Daphnis E, Goulielmos G, Loizou P, Savige J, Höhne M, Völker LA, Benzing T, Maxwell PH, Gale DP, Gorski M, Böger C, Kollerits B, Kronenberg F, Paulweber B, Zavros M, Pierides A, Deltas C. Voskarides K, et al. Among authors: benzing t. PLoS One. 2017 Mar 23;12(3):e0174274. doi: 10.1371/journal.pone.0174274. eCollection 2017. PLoS One. 2017. PMID: 28334007 Free PMC article.
Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.
Liebau MC, Höpker K, Müller RU, Schmedding I, Zank S, Schairer B, Fabretti F, Höhne M, Bartram MP, Dafinger C, Hackl M, Burst V, Habbig S, Zentgraf H, Blaukat A, Walz G, Benzing T, Schermer B. Liebau MC, et al. Among authors: benzing t. J Biol Chem. 2011 Apr 22;286(16):14237-45. doi: 10.1074/jbc.M110.165464. Epub 2011 Feb 28. J Biol Chem. 2011. PMID: 21357692 Free PMC article.
Comparative analysis of Neph gene expression in mouse and chicken development.
Völker LA, Petry M, Abdelsabour-Khalaf M, Schweizer H, Yusuf F, Busch T, Schermer B, Benzing T, Brand-Saberi B, Kretz O, Höhne M, Kispert A. Völker LA, et al. Among authors: benzing t. Histochem Cell Biol. 2012 Mar;137(3):355-66. doi: 10.1007/s00418-011-0903-2. Epub 2011 Dec 29. Histochem Cell Biol. 2012. PMID: 22205279 Free PMC article.
Survival and distribution of injected haematopoietic stem cells in acute kidney injury.
Burst V, Pütsch F, Kubacki T, Völker LA, Bartram MP, Müller RU, Gillis M, Kurschat CE, Grundmann F, Müller-Ehmsen J, Benzing T, Teschner S. Burst V, et al. Among authors: benzing t. Nephrol Dial Transplant. 2013 May;28(5):1131-9. doi: 10.1093/ndt/gfs513. Epub 2012 Nov 29. Nephrol Dial Transplant. 2013. PMID: 23197679
A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin.
Schurek EM, Völker LA, Tax J, Lamkemeyer T, Rinschen MM, Ungrue D, Kratz JE 3rd, Sirianant L, Kunzelmann K, Chalfie M, Schermer B, Benzing T, Höhne M. Schurek EM, et al. Among authors: benzing t. J Biol Chem. 2014 Apr 18;289(16):11262-11271. doi: 10.1074/jbc.M113.521773. Epub 2014 Mar 4. J Biol Chem. 2014. PMID: 24596097 Free PMC article.
Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure.
Ising C, Koehler S, Brähler S, Merkwirth C, Höhne M, Baris OR, Hagmann H, Kann M, Fabretti F, Dafinger C, Bloch W, Schermer B, Linkermann A, Brüning JC, Kurschat CE, Müller RU, Wiesner RJ, Langer T, Benzing T, Brinkkoetter PT. Ising C, et al. Among authors: benzing t. EMBO Mol Med. 2015 Mar;7(3):275-87. doi: 10.15252/emmm.201404916. EMBO Mol Med. 2015. PMID: 25643582 Free PMC article.
The NF-κB essential modulator (NEMO) controls podocyte cytoskeletal dynamics independently of NF-κB.
Brähler S, Ising C, Barrera Aranda B, Höhne M, Schermer B, Benzing T, Brinkkoetter PT. Brähler S, et al. Among authors: benzing t. Am J Physiol Renal Physiol. 2015 Oct 1;309(7):F617-26. doi: 10.1152/ajprenal.00059.2015. Epub 2015 Aug 12. Am J Physiol Renal Physiol. 2015. PMID: 26268269 Free article.
As previously published, genetic inhibition of the NF-kappaB essential modulator (NEMO) in podocytes does not affect glomerular function under physiological, nonstressed conditions nor does it alter the initial podocyte response in an experimental glomerulonephritis (NTN) model ( …
As previously published, genetic inhibition of the NF-kappaB essential modulator (NEMO) in podocytes does not affect glomerular function und …
281 results