Branford S - Search Results

1

The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1.

Wylie AA, Schoepfer J, Jahnke W, Cowan-Jacob SW, Loo A, Furet P, Marzinzik AL, Pelle X, Donovan J, Zhu W, Buonamici S, Hassan AQ, Lombardo F, Iyer V, Palmer M, Berellini G, Dodd S, Thohan S, Bitter H, Branford S, Ross DM, Hughes TP, Petruzzelli L, Vanasse KG, Warmuth M, Hofmann F, Keen NJ, Sellers WR. Wylie AA, et al. Among authors: branford s. Nature. 2017 Mar 30;543(7647):733-737. doi: 10.1038/nature21702. Epub 2017 Mar 22. Nature. 2017. PMID: 28329763

2

Monitoring chronic myeloid leukaemia therapy by real-time quantitative PCR in blood is a reliable alternative to bone marrow cytogenetics.

Branford S, Hughes TP, Rudzki Z. Branford S, et al. Br J Haematol. 1999 Dec;107(3):587-99. doi: 10.1046/j.1365-2141.1999.01749.x. Br J Haematol. 1999. PMID: 10583264 Free article.

3

A novel BCR-ABL transcript (e8a2) with the insertion of an inverted sequence of ABL intron 1b in a patient with Philadelphia-positive chronic myeloid leukaemia.

Branford S, Rudzki Z, Hughes TP. Branford S, et al. Br J Haematol. 2000 Jun;109(3):635-7. doi: 10.1046/j.1365-2141.2000.02042.x. Br J Haematol. 2000. PMID: 10886215 Free article.

4

High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance.

Branford S, Rudzki Z, Walsh S, Grigg A, Arthur C, Taylor K, Herrmann R, Lynch KP, Hughes TP. Branford S, et al. Blood. 2002 May 1;99(9):3472-5. doi: 10.1182/blood.v99.9.3472. Blood. 2002. PMID: 11964322 Free article.

5

Dual transcription of b2a2 and b3a2 BCR-ABL transcripts in chronic myeloid leukaemia is confined to patients with a linked polymorphism within the BCR gene.

Branford S, Hughes TP, Rudzki Z. Branford S, et al. Br J Haematol. 2002 Jun;117(4):875-7. doi: 10.1046/j.1365-2141.2002.03508.x. Br J Haematol. 2002. PMID: 12060123 Free article.

6

Successful peripheral blood stem cell mobilisation with filgrastim in patients with chronic myeloid leukaemia achieving complete cytogenetic response with imatinib, without increasing disease burden as measured by quantitative real-time PCR.

Hui CH, Goh KY, White D, Branford S, Grigg A, Seymour JF, Kwan YL, Walsh S, Hoyt R, Trickett A, Rudzki B, Ma DD, To LB, Hughes TP. Hui CH, et al. Among authors: branford s. Leukemia. 2003 May;17(5):821-8. doi: 10.1038/sj.leu.2402917. Leukemia. 2003. PMID: 12750692

7

Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase.

Branford S, Rudzki Z, Harper A, Grigg A, Taylor K, Durrant S, Arthur C, Browett P, Schwarer AP, Ma D, Seymour JF, Bradstock K, Joske D, Lynch K, Gathmann I, Hughes TP. Branford S, et al. Leukemia. 2003 Dec;17(12):2401-9. doi: 10.1038/sj.leu.2403158. Leukemia. 2003. PMID: 14523461 Clinical Trial.

8

In vitro sensitivity to imatinib-induced inhibition of ABL kinase activity is predictive of molecular response in patients with de novo CML.

White D, Saunders V, Lyons AB, Branford S, Grigg A, To LB, Hughes T. White D, et al. Among authors: branford s. Blood. 2005 Oct 1;106(7):2520-6. doi: 10.1182/blood-2005-03-1103. Epub 2005 Jun 14. Blood. 2005. PMID: 15956284 Free article.

9

Dynamics of chronic myeloid leukaemia.

Michor F, Hughes TP, Iwasa Y, Branford S, Shah NP, Sawyers CL, Nowak MA. Michor F, et al. Among authors: branford s. Nature. 2005 Jun 30;435(7046):1267-70. doi: 10.1038/nature03669. Nature. 2005. PMID: 15988530

10

Molecular monitoring of BCR-ABL as a guide to clinical management in chronic myeloid leukaemia.

Hughes T, Branford S. Hughes T, et al. Among authors: branford s. Blood Rev. 2006 Jan;20(1):29-41. doi: 10.1016/j.blre.2005.01.008. Epub 2005 Mar 2. Blood Rev. 2006. PMID: 16426942 Review.

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