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Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.
Guitart X, Navarro G, Moreno E, Yano H, Cai NS, Sánchez-Soto M, Kumar-Barodia S, Naidu YT, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, McCormick PJ, Ferré S. Guitart X, et al. Among authors: yano h. Mol Pharmacol. 2014 Oct;86(4):417-29. doi: 10.1124/mol.114.093096. Epub 2014 Aug 5. Mol Pharmacol. 2014. PMID: 25097189 Free PMC article.
Synthesis and biological evaluation of a novel series of heterobivalent muscarinic ligands based on xanomeline and 1-[3-(4-butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1).
Bonifazi A, Yano H, Del Bello F, Farande A, Quaglia W, Petrelli R, Matucci R, Nesi M, Vistoli G, Ferré S, Piergentili A. Bonifazi A, et al. Among authors: yano h. J Med Chem. 2014 Nov 13;57(21):9065-77. doi: 10.1021/jm501173q. Epub 2014 Oct 16. J Med Chem. 2014. PMID: 25275964
Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors.
Cao J, Slack RD, Bakare OM, Burzynski C, Rais R, Slusher BS, Kopajtic T, Bonifazi A, Ellenberger MP, Yano H, He Y, Bi GH, Xi ZX, Loland CJ, Newman AH. Cao J, et al. Among authors: yano h. J Med Chem. 2016 Dec 8;59(23):10676-10691. doi: 10.1021/acs.jmedchem.6b01373. Epub 2016 Nov 28. J Med Chem. 2016. PMID: 27933960 Free PMC article.
Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor.
Michino M, Boateng CA, Donthamsetti P, Yano H, Bakare OM, Bonifazi A, Ellenberger MP, Keck TM, Kumar V, Zhu C, Verma R, Deschamps JR, Javitch JA, Newman AH, Shi L. Michino M, et al. Among authors: yano h. J Med Chem. 2017 Jan 26;60(2):580-593. doi: 10.1021/acs.jmedchem.6b01148. Epub 2017 Jan 5. J Med Chem. 2017. PMID: 27983845 Free PMC article.
2,027 results