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Page 1
Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy.
Stapel B, Kohlhaas M, Ricke-Hoch M, Haghikia A, Erschow S, Knuuti J, Silvola JM, Roivainen A, Saraste A, Nickel AG, Saar JA, Sieve I, Pietzsch S, Müller M, Bogeski I, Kappl R, Jauhiainen M, Thackeray JT, Scherr M, Bengel FM, Hagl C, Tudorache I, Bauersachs J, Maack C, Hilfiker-Kleiner D. Stapel B, et al. Eur Heart J. 2017 Feb 1;38(5):349-361. doi: 10.1093/eurheartj/ehw086. Eur Heart J. 2017. PMID: 28201733 Free PMC article.
Many good reasons to have STAT3 in the heart.
Hilfiker-Kleiner D, Hilfiker A, Drexler H. Hilfiker-Kleiner D, et al. Pharmacol Ther. 2005 Jul;107(1):131-7. doi: 10.1016/j.pharmthera.2005.02.003. Epub 2005 Apr 21. Pharmacol Ther. 2005. PMID: 15963355 Review.
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy.
Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, Forster O, Quint A, Landmesser U, Doerries C, Luchtefeld M, Poli V, Schneider MD, Balligand JL, Desjardins F, Ansari A, Struman I, Nguyen NQ, Zschemisch NH, Klein G, Heusch G, Schulz R, Hilfiker A, Drexler H. Hilfiker-Kleiner D, et al. Cell. 2007 Feb 9;128(3):589-600. doi: 10.1016/j.cell.2006.12.036. Cell. 2007. PMID: 17289576 Free article. Clinical Trial.
STAT3 and cardiac remodeling.
Haghikia A, Stapel B, Hoch M, Hilfiker-Kleiner D. Haghikia A, et al. Heart Fail Rev. 2011 Jan;16(1):35-47. doi: 10.1007/s10741-010-9170-x. Heart Fail Rev. 2011. PMID: 20407820 Review.
Continuous glycoprotein-130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction.
Hilfiker-Kleiner D, Shukla P, Klein G, Schaefer A, Stapel B, Hoch M, Müller W, Scherr M, Theilmeier G, Ernst M, Hilfiker A, Drexler H. Hilfiker-Kleiner D, et al. Circulation. 2010 Jul 13;122(2):145-55. doi: 10.1161/CIRCULATIONAHA.109.933127. Epub 2010 Jun 28. Circulation. 2010. PMID: 20585009
232 results