Kahn CR - Search Results

1

Adipose-derived circulating miRNAs regulate gene expression in other tissues.

Thomou T, Mori MA, Dreyfuss JM, Konishi M, Sakaguchi M, Wolfrum C, Rao TN, Winnay JN, Garcia-Martin R, Grinspoon SK, Gorden P, Kahn CR. Thomou T, et al. Among authors: kahn cr. Nature. 2017 Feb 23;542(7642):450-455. doi: 10.1038/nature21365. Epub 2017 Feb 15. Nature. 2017. PMID: 28199304 Free PMC article.

2

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

Araki E, Lipes MA, Patti ME, Brüning JC, Haag B 3rd, Johnson RS, Kahn CR. Araki E, et al. Among authors: kahn cr. Nature. 1994 Nov 10;372(6502):186-90. doi: 10.1038/372186a0. Nature. 1994. PMID: 7526222

3

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells.

Brüning JC, Winnay J, Cheatham B, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Mol Cell Biol. 1997 Mar;17(3):1513-21. doi: 10.1128/MCB.17.3.1513. Mol Cell Biol. 1997. PMID: 9032279 Free PMC article.

4

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles.

Brüning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Cell. 1997 Feb 21;88(4):561-72. doi: 10.1016/s0092-8674(00)81896-6. Cell. 1997. PMID: 9038347 Free article.

5

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance.

Brüning JC, Michael MD, Winnay JN, Hayashi T, Hörsch D, Accili D, Goodyear LJ, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Mol Cell. 1998 Nov;2(5):559-69. doi: 10.1016/s1097-2765(00)80155-0. Mol Cell. 1998. PMID: 9844629 Free article.

6

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: kahn cr. Cell. 1999 Feb 5;96(3):329-39. doi: 10.1016/s0092-8674(00)80546-2. Cell. 1999. PMID: 10025399 Free article.

7

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.

Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, Kahn CR. Kulkarni RN, et al. Among authors: kahn cr. J Clin Invest. 1999 Dec;104(12):R69-75. doi: 10.1172/JCI8339. J Clin Invest. 1999. PMID: 10606633 Free PMC article.

8

Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts.

Winnay JN, Brüning JC, Burks DJ, Kahn CR. Winnay JN, et al. Among authors: kahn cr. J Biol Chem. 2000 Apr 7;275(14):10545-50. doi: 10.1074/jbc.275.14.10545. J Biol Chem. 2000. PMID: 10744748 Free article.

9

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

Zisman A, Peroni OD, Abel ED, Michael MD, Mauvais-Jarvis F, Lowell BB, Wojtaszewski JF, Hirshman MF, Virkamaki A, Goodyear LJ, Kahn CR, Kahn BB. Zisman A, et al. Among authors: kahn bb, kahn cr. Nat Med. 2000 Aug;6(8):924-8. doi: 10.1038/78693. Nat Med. 2000. PMID: 10932232

10

A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes.

Mauvais-Jarvis F, Virkamaki A, Michael MD, Winnay JN, Zisman A, Kulkarni RN, Kahn CR. Mauvais-Jarvis F, et al. Among authors: kahn cr. Diabetes. 2000 Dec;49(12):2126-34. doi: 10.2337/diabetes.49.12.2126. Diabetes. 2000. PMID: 11118016

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