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The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P. Baroja-Mazo A, et al. Among authors: pelegrin p. Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952504
Involvement of P2X7 receptor in neuronal degeneration triggered by traumatic injury.
Nadal-Nicolás FM, Galindo-Romero C, Valiente-Soriano FJ, Barberà-Cremades M, deTorre-Minguela C, Salinas-Navarro M, Pelegrín P, Agudo-Barriuso M. Nadal-Nicolás FM, et al. Among authors: pelegrin p. Sci Rep. 2016 Dec 8;6:38499. doi: 10.1038/srep38499. Sci Rep. 2016. PMID: 27929040 Free PMC article.
Inflammasomes in Liver Fibrosis.
Alegre F, Pelegrin P, Feldstein AE. Alegre F, et al. Among authors: pelegrin p. Semin Liver Dis. 2017 May;37(2):119-127. doi: 10.1055/s-0037-1601350. Epub 2017 May 31. Semin Liver Dis. 2017. PMID: 28564720 Review.
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever.
Moghaddas F, Llamas R, De Nardo D, Martinez-Banaclocha H, Martinez-Garcia JJ, Mesa-Del-Castillo P, Baker PJ, Gargallo V, Mensa-Vilaro A, Canna S, Wicks IP, Pelegrin P, Arostegui JI, Masters SL. Moghaddas F, et al. Among authors: pelegrin p. Ann Rheum Dis. 2017 Dec;76(12):2085-2094. doi: 10.1136/annrheumdis-2017-211473. Epub 2017 Aug 23. Ann Rheum Dis. 2017. PMID: 28835462 Free PMC article.
Late-Onset Cryopyrin-Associated Periodic Syndromes Caused by Somatic NLRP3 Mosaicism-UK Single Center Experience.
Rowczenio DM, Gomes SM, Aróstegui JI, Mensa-Vilaro A, Omoyinmi E, Trojer H, Baginska A, Baroja-Mazo A, Pelegrin P, Savic S, Lane T, Williams R, Brogan P, Lachmann HJ, Hawkins PN. Rowczenio DM, et al. Among authors: pelegrin p. Front Immunol. 2017 Oct 31;8:1410. doi: 10.3389/fimmu.2017.01410. eCollection 2017. Front Immunol. 2017. PMID: 29163488 Free PMC article.
151 results