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Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes.
Nykjaer A, Petersen CM, Møller B, Jensen PH, Moestrup SK, Holtet TL, Etzerodt M, Thøgersen HC, Munch M, Andreasen PA, et al. Nykjaer A, et al. Among authors: andreasen pa. J Biol Chem. 1992 Jul 25;267(21):14543-6. J Biol Chem. 1992. PMID: 1378833 Free article.
Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a region of the alpha 2-macroglobulin receptor containing a cluster of eight complement-type repeats.
Moestrup SK, Holtet TL, Etzerodt M, Thøgersen HC, Nykjaer A, Andreasen PA, Rasmussen HH, Sottrup-Jensen L, Gliemann J. Moestrup SK, et al. Among authors: andreasen pa. J Biol Chem. 1993 Jun 25;268(18):13691-6. J Biol Chem. 1993. PMID: 7685767 Free article.
The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.
Gliemann J, Hermey G, Nykjaer A, Petersen CM, Jacobsen C, Andreasen PA. Gliemann J, et al. Among authors: andreasen pa. Biochem J. 2004 Jul 1;381(Pt 1):203-12. doi: 10.1042/BJ20040149. Biochem J. 2004. PMID: 15053742 Free PMC article.
Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis.
Skeldal S, Larsen JV, Pedersen KE, Petersen HH, Egelund R, Christensen A, Jensen JK, Gliemann J, Andreasen PA. Skeldal S, et al. Among authors: andreasen pa. FEBS J. 2006 Nov;273(22):5143-59. doi: 10.1111/j.1742-4658.2006.05511.x. Epub 2006 Oct 17. FEBS J. 2006. PMID: 17042782 Free article.
192 results