Luo J - Search Results

1

Mouse species-specific control of hepatocarcinogenesis and metabolism by FGF19/FGF15.

Zhou M, Luo J, Chen M, Yang H, Learned RM, DePaoli AM, Tian H, Ling L. Zhou M, et al. Among authors: luo j. J Hepatol. 2017 Jun;66(6):1182-1192. doi: 10.1016/j.jhep.2017.01.027. Epub 2017 Feb 9. J Hepatol. 2017. PMID: 28189755 Free article.

2

A nontumorigenic variant of FGF19 treats cholestatic liver diseases.

Luo J, Ko B, Elliott M, Zhou M, Lindhout DA, Phung V, To C, Learned RM, Tian H, DePaoli AM, Ling L. Luo J, et al. Sci Transl Med. 2014 Jul 30;6(247):247ra100. doi: 10.1126/scitranslmed.3009098. Sci Transl Med. 2014. PMID: 25080475 Clinical Trial.

3

Apelin-36 Modulates Blood Glucose and Body Weight Independently of Canonical APJ Receptor Signaling.

Galon-Tilleman H, Yang H, Bednarek MA, Spurlock SM, Paavola KJ, Ko B, To C, Luo J, Tian H, Jermutus L, Grimsby J, Rondinone CM, Konkar A, Kaplan DD. Galon-Tilleman H, et al. Among authors: luo j. J Biol Chem. 2017 Feb 3;292(5):1925-1933. doi: 10.1074/jbc.M116.748103. Epub 2016 Dec 19. J Biol Chem. 2017. PMID: 27994053 Free PMC article.

4

AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents.

Lin DC, Zhang J, Zhuang R, Li F, Nguyen K, Chen M, Tran T, Lopez E, Lu JY, Li XN, Tang L, Tonn GR, Swaminath G, Reagan JD, Chen JL, Tian H, Lin YJ, Houze JB, Luo J. Lin DC, et al. Among authors: luo j. PLoS One. 2011;6(11):e27270. doi: 10.1371/journal.pone.0027270. Epub 2011 Nov 8. PLoS One. 2011. PMID: 22087278 Free PMC article.

5

AMG 837: a potent, orally bioavailable GPR40 agonist.

Houze JB, Zhu L, Sun Y, Akerman M, Qiu W, Zhang AJ, Sharma R, Schmitt M, Wang Y, Liu J, Liu J, Medina JC, Reagan JD, Luo J, Tonn G, Zhang J, Lu JY, Chen M, Lopez E, Nguyen K, Yang L, Tang L, Tian H, Shuttleworth SJ, Lin DC. Houze JB, et al. Among authors: luo j. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1267-70. doi: 10.1016/j.bmcl.2011.10.118. Epub 2011 Nov 6. Bioorg Med Chem Lett. 2012. PMID: 22217876

6

A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents.

Luo J, Swaminath G, Brown SP, Zhang J, Guo Q, Chen M, Nguyen K, Tran T, Miao L, Dransfield PJ, Vimolratana M, Houze JB, Wong S, Toteva M, Shan B, Li F, Zhuang R, Lin DC. Luo J, et al. PLoS One. 2012;7(10):e46300. doi: 10.1371/journal.pone.0046300. Epub 2012 Oct 9. PLoS One. 2012. PMID: 23056280 Free PMC article.

7

Evaluating insulin secretagogues in a humanized mouse model with functional human islets.

Luo J, Nguyen K, Chen M, Tran T, Hao J, Tian B, Rulifson IC, Zhang Y, Tian L, Zhang Y, Lopez E, Lin DC, Wang Y, Ma Z, Houze J, Guo Z. Luo J, et al. Metabolism. 2013 Jan;62(1):90-9. doi: 10.1016/j.metabol.2012.07.010. Epub 2012 Sep 13. Metabolism. 2013. PMID: 22982177

8

Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis.

Gadaleta RM, Scialpi N, Peres C, Cariello M, Ko B, Luo J, Porru E, Roda A, Sabbà C, Moschetta A. Gadaleta RM, et al. Among authors: luo j. Sci Rep. 2018 Nov 21;8(1):17210. doi: 10.1038/s41598-018-35496-z. Sci Rep. 2018. PMID: 30464200 Free PMC article.

9

Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor.

Lin DC, Guo Q, Luo J, Zhang J, Nguyen K, Chen M, Tran T, Dransfield PJ, Brown SP, Houze J, Vimolratana M, Jiao XY, Wang Y, Birdsall NJ, Swaminath G. Lin DC, et al. Among authors: luo j. Mol Pharmacol. 2012 Nov;82(5):843-59. doi: 10.1124/mol.112.079640. Epub 2012 Aug 2. Mol Pharmacol. 2012. PMID: 22859723 Free PMC article.

10

Circulating FGF19 closely correlates with bile acid synthesis and cholestasis in patients with primary biliary cirrhosis.

Li Z, Lin B, Lin G, Wu Y, Jie Y, Li X, Ko B, Chong Y, Luo J. Li Z, et al. Among authors: luo j. PLoS One. 2017 Jun 1;12(6):e0178580. doi: 10.1371/journal.pone.0178580. eCollection 2017. PLoS One. 2017. PMID: 28570655 Free PMC article.

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