Yim M - Search Results

1

Taming hyperactive hDNase I: Stable inducible expression of a hyperactive salt- and actin-resistant variant of human deoxyribonuclease I in CHO cells.

Lam C, Santell L, Wilson B, Yim M, Louie S, Tang D, Shaw D, Chan P, Lazarus RA, Snedecor B, Misaghi S. Lam C, et al. Among authors: yim m. Biotechnol Prog. 2017 Mar;33(2):523-533. doi: 10.1002/btpr.2439. Epub 2017 Feb 6. Biotechnol Prog. 2017. PMID: 28127892

2

FX knockout CHO hosts can express desired ratios of fucosylated or afucosylated antibodies with high titers and comparable product quality.

Louie S, Haley B, Marshall B, Heidersbach A, Yim M, Brozynski M, Tang D, Lam C, Petryniak B, Shaw D, Shim J, Miller A, Lowe JB, Snedecor B, Misaghi S. Louie S, et al. Among authors: yim m. Biotechnol Bioeng. 2017 Mar;114(3):632-644. doi: 10.1002/bit.26188. Epub 2016 Oct 4. Biotechnol Bioeng. 2017. PMID: 27666939

3

Evaluation of heavy chain C-terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells.

Hu Z, Tang D, Misaghi S, Jiang G, Yu C, Yim M, Shaw D, Snedecor B, Laird MW, Shen A. Hu Z, et al. Among authors: yim m. Biotechnol Prog. 2017 May;33(3):786-794. doi: 10.1002/btpr.2444. Epub 2017 Mar 24. Biotechnol Prog. 2017. PMID: 28188688

4

Supplementation of Nucleosides During Selection can Reduce Sequence Variant Levels in CHO Cells Using GS/MSX Selection System.

Tang D, Lam C, Louie S, Hoi KH, Shaw D, Yim M, Snedecor B, Misaghi S. Tang D, et al. Among authors: yim m. Biotechnol J. 2018 Jan;13(1). doi: 10.1002/biot.201700335. Epub 2017 Aug 17. Biotechnol J. 2018. PMID: 28745430

5

Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not.

Zhou Y, Shaw D, Lam C, Tsukuda J, Yim M, Tang D, Louie S, Laird MW, Snedecor B, Misaghi S. Zhou Y, et al. Among authors: yim m. Biotechnol Prog. 2018 May;34(3):559-569. doi: 10.1002/btpr.2560. Epub 2017 Oct 9. Biotechnol Prog. 2018. PMID: 28941017

6

Development and characterization of an automated imaging workflow to generate clonally-derived cell lines for therapeutic proteins.

Shaw D, Yim M, Tsukuda J, Joly JC, Lin A, Snedecor B, Laird MW, Lang SE. Shaw D, et al. Among authors: yim m. Biotechnol Prog. 2018 May;34(3):584-592. doi: 10.1002/btpr.2561. Epub 2017 Oct 10. Biotechnol Prog. 2018. PMID: 28960825

7

Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality.

Ko P, Misaghi S, Hu Z, Zhan D, Tsukuda J, Yim M, Sanford M, Shaw D, Shiratori M, Snedecor B, Laird M, Shen A. Ko P, et al. Among authors: yim m. Biotechnol Prog. 2018 May;34(3):624-634. doi: 10.1002/btpr.2594. Epub 2017 Dec 27. Biotechnol Prog. 2018. PMID: 29226566

8

Achieving greater efficiency and higher confidence in single-cell cloning by combining cell printing and plate imaging technologies.

Yim M, Shaw D. Yim M, et al. Biotechnol Prog. 2018 Nov;34(6):1454-1459. doi: 10.1002/btpr.2698. Epub 2018 Oct 3. Biotechnol Prog. 2018. PMID: 30281954

9

Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum-free media.

Louie S, Heidersbach A, Blanco N, Haley B, Rose CM, Liu PS, Yim M, Tang D, Lam C, Sandoval WN, Shaw D, Snedecor B, Misaghi S. Louie S, et al. Among authors: yim m. Biotechnol Prog. 2020 May;36(3):e2951. doi: 10.1002/btpr.2951. Epub 2020 Jan 2. Biotechnol Prog. 2020. PMID: 31846224

10

Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position.

Carver J, Ng D, Zhou M, Ko P, Zhan D, Yim M, Shaw D, Snedecor B, Laird MW, Lang S, Shen A, Hu Z. Carver J, et al. Among authors: yim m. Biotechnol Prog. 2020 Jul;36(4):e2967. doi: 10.1002/btpr.2967. Epub 2020 Feb 17. Biotechnol Prog. 2020. PMID: 31965756

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