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JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome.
Del Bel KL, Ragotte RJ, Saferali A, Lee S, Vercauteren SM, Mostafavi SA, Schreiber RA, Prendiville JS, Phang MS, Halparin J, Au N, Dean JM, Priatel JJ, Jewels E, Junker AK, Rogers PC, Seear M, McKinnon ML, Turvey SE. Del Bel KL, et al. Among authors: mostafavi sa. J Allergy Clin Immunol. 2017 Jun;139(6):2016-2020.e5. doi: 10.1016/j.jaci.2016.12.957. Epub 2017 Jan 19. J Allergy Clin Immunol. 2017. PMID: 28111307 No abstract available.
Deep learning of immune cell differentiation.
Maslova A, Ramirez RN, Ma K, Schmutz H, Wang C, Fox C, Ng B, Benoist C, Mostafavi S; Immunological Genome Project. Maslova A, et al. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25655-25666. doi: 10.1073/pnas.2011795117. Epub 2020 Sep 25. Proc Natl Acad Sci U S A. 2020. PMID: 32978299 Free PMC article.
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes.
Kiner E, Willie E, Vijaykumar B, Chowdhary K, Schmutz H, Chandler J, Schnell A, Thakore PI, LeGros G, Mostafavi S, Mathis D, Benoist C; Immunological Genome Project Consortium. Kiner E, et al. Nat Immunol. 2021 Feb;22(2):216-228. doi: 10.1038/s41590-020-00836-7. Epub 2021 Jan 18. Nat Immunol. 2021. PMID: 33462454 Free PMC article.
Biological embedding of experience: A primer on epigenetics.
Aristizabal MJ, Anreiter I, Halldorsdottir T, Odgers CL, McDade TW, Goldenberg A, Mostafavi S, Kobor MS, Binder EB, Sokolowski MB, O'Donnell KJ. Aristizabal MJ, et al. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23261-23269. doi: 10.1073/pnas.1820838116. Epub 2019 Oct 17. Proc Natl Acad Sci U S A. 2020. PMID: 31624126 Free PMC article. Review.
125 results