Kopljar I - Search Results

1

Chronic drug-induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell-derived cardiomyocytes.

Kopljar I, De Bondt A, Vinken P, Teisman A, Damiano B, Goeminne N, Van den Wyngaert I, Gallacher DJ, Lu HR. Kopljar I, et al. Br J Pharmacol. 2017 Nov;174(21):3766-3779. doi: 10.1111/bph.13713. Epub 2017 Feb 8. Br J Pharmacol. 2017. PMID: 28094846 Free PMC article.

2

Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias.

Lu HR, Hortigon-Vinagre MP, Zamora V, Kopljar I, De Bondt A, Gallacher DJ, Smith G. Lu HR, et al. Among authors: kopljar i. J Pharmacol Toxicol Methods. 2017 Sep;87:53-67. doi: 10.1016/j.vascn.2017.05.001. Epub 2017 May 10. J Pharmacol Toxicol Methods. 2017. PMID: 28501647

3

Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model.

Van de Sande DV, Kopljar I, Teisman A, Gallacher DJ, Snyders DJ, Lu HR, Labro AJ. Van de Sande DV, et al. Among authors: kopljar i. Front Pharmacol. 2019 Dec 11;10:1374. doi: 10.3389/fphar.2019.01374. eCollection 2019. Front Pharmacol. 2019. PMID: 31920633 Free PMC article.

4

Functional and Transcriptional Characterization of Histone Deacetylase Inhibitor-Mediated Cardiac Adverse Effects in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Kopljar I, Gallacher DJ, De Bondt A, Cougnaud L, Vlaminckx E, Van den Wyngaert I, Lu HR. Kopljar I, et al. Stem Cells Transl Med. 2016 May;5(5):602-12. doi: 10.5966/sctm.2015-0279. Epub 2016 Mar 31. Stem Cells Transl Med. 2016. PMID: 27034410 Free PMC article.

5

Impact of calcium-sensitive dyes on the beating properties and pharmacological responses of human iPS-derived cardiomyocytes using the calcium transient assay.

Kopljar I, Hermans AN, Teisman A, Gallacher DJ, Lu HR. Kopljar I, et al. J Pharmacol Toxicol Methods. 2018 May-Jun;91:80-86. doi: 10.1016/j.vascn.2018.02.004. Epub 2018 Feb 6. J Pharmacol Toxicol Methods. 2018. PMID: 29421525

6

Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking.

Kopljar I, Lu HR, Van Ammel K, Otava M, Tekle F, Teisman A, Gallacher DJ. Kopljar I, et al. Stem Cell Reports. 2018 Dec 11;11(6):1365-1377. doi: 10.1016/j.stemcr.2018.11.007. Stem Cell Reports. 2018. PMID: 30540961 Free PMC article.

7

Assessing Drug-Induced Long QT and Proarrhythmic Risk Using Human Stem-Cell-Derived Cardiomyocytes in a Ca2+ Imaging Assay: Evaluation of 28 CiPA Compounds at Three Test Sites.

Lu HR, Zeng H, Kettenhofen R, Guo L, Kopljar I, van Ammel K, Tekle F, Teisman A, Zhai J, Clouse H, Pierson J, Furniss M, Lagrutta A, Sannajust F, Gallacher DJ. Lu HR, et al. Among authors: kopljar i. Toxicol Sci. 2019 Aug 1;170(2):345-356. doi: 10.1093/toxsci/kfz102. Toxicol Sci. 2019. PMID: 31020317 Free PMC article.

8

[No title available]

[No authors listed] [No authors listed] PMID: 31962934

9

The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells.

Van de Sande DV, Kopljar I, Maaike A, Teisman A, Gallacher DJ, Bart L, Snyders DJ, Leybaert L, Lu HR, Labro AJ. Van de Sande DV, et al. Among authors: kopljar i. Channels (Austin). 2021 Dec;15(1):239-252. doi: 10.1080/19336950.2021.1871815. Channels (Austin). 2021. PMID: 33465001 Free PMC article.

10

[No title available]

[No authors listed] [No authors listed] PMID: 31962972

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