Zheng Z - Search Results

1

Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis.

Wang X, Zheng Z, Caviglia JM, Corey KE, Herfel TM, Cai B, Masia R, Chung RT, Lefkowitch JH, Schwabe RF, Tabas I. Wang X, et al. Among authors: zheng z. Cell Metab. 2016 Dec 13;24(6):848-862. doi: 10.1016/j.cmet.2016.09.016. Epub 2016 Oct 27. Cell Metab. 2016. PMID: 28068223 Free PMC article.

2

Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance.

Ozcan L, Ghorpade DS, Zheng Z, de Souza JC, Chen K, Bessler M, Bagloo M, Schrope B, Pestell R, Tabas I. Ozcan L, et al. Among authors: zheng z. Cell Rep. 2016 Jun 7;15(10):2214-2225. doi: 10.1016/j.celrep.2016.05.006. Epub 2016 May 26. Cell Rep. 2016. PMID: 27239042 Free PMC article.

3

CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis.

Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I. Doran AC, et al. Among authors: zheng z. J Clin Invest. 2017 Nov 1;127(11):4075-4089. doi: 10.1172/JCI94735. Epub 2017 Oct 3. J Clin Invest. 2017. PMID: 28972541 Free PMC article.

4

Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.

Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Blüher M, Czech MP, Tabas I. Ghorpade DS, et al. Among authors: zheng z. Nature. 2018 Mar 29;555(7698):673-677. doi: 10.1038/nature26138. Epub 2018 Mar 21. Nature. 2018. PMID: 29562231 Free PMC article.

5

An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1.

Zheng Z, Nayak L, Wang W, Yurdagul A Jr, Wang X, Cai B, Lapping S, Ozcan L, Ramakrishnan R, Pestell RG, Jain MK, Tabas I. Zheng Z, et al. Blood. 2019 Feb 14;133(7):743-753. doi: 10.1182/blood-2018-07-864843. Epub 2018 Dec 1. Blood. 2019. PMID: 30504459 Free PMC article.

6

Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis.

Cai B, Dongiovanni P, Corey KE, Wang X, Shmarakov IO, Zheng Z, Kasikara C, Davra V, Meroni M, Chung RT, Rothlin CV, Schwabe RF, Blaner WS, Birge RB, Valenti L, Tabas I. Cai B, et al. Among authors: zheng z. Cell Metab. 2020 Feb 4;31(2):406-421.e7. doi: 10.1016/j.cmet.2019.11.013. Epub 2019 Dec 12. Cell Metab. 2020. PMID: 31839486 Free PMC article.

7

Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury.

Yurdagul A Jr, Subramanian M, Wang X, Crown SB, Ilkayeva OR, Darville L, Kolluru GK, Rymond CC, Gerlach BD, Zheng Z, Kuriakose G, Kevil CG, Koomen JM, Cleveland JL, Muoio DM, Tabas I. Yurdagul A Jr, et al. Among authors: zheng z. Cell Metab. 2020 Mar 3;31(3):518-533.e10. doi: 10.1016/j.cmet.2020.01.001. Epub 2020 Jan 30. Cell Metab. 2020. PMID: 32004476 Free PMC article.

8

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.

Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Wang X, et al. Among authors: zheng z. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. Cell Metab. 2020. PMID: 32259482 Free PMC article.

9

Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity.

Zheng Z, Nakamura K, Gershbaum S, Wang X, Thomas S, Bessler M, Schrope B, Krikhely A, Liu RM, Ozcan L, López JA, Tabas I. Zheng Z, et al. J Clin Invest. 2020 Aug 3;130(8):4348-4359. doi: 10.1172/JCI135919. J Clin Invest. 2020. PMID: 32657780 Free PMC article.

10

Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis.

Kasikara C, Schilperoort M, Gerlach B, Xue C, Wang X, Zheng Z, Kuriakose G, Dorweiler B, Zhang H, Fredman G, Saleheen D, Reilly MP, Tabas I. Kasikara C, et al. Among authors: zheng z. J Clin Invest. 2021 Apr 15;131(8):e145275. doi: 10.1172/JCI145275. J Clin Invest. 2021. PMID: 33630758 Free PMC article.

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