Prescher H - Search Results

1

Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural products.

Prescher H, Koch G, Schuhmann T, Ertl P, Bussenault A, Glick M, Dix I, Petersen F, Lizos DE. Prescher H, et al. Bioorg Med Chem. 2017 Feb 1;25(3):921-925. doi: 10.1016/j.bmc.2016.12.005. Epub 2016 Dec 8. Bioorg Med Chem. 2017. PMID: 28011199

2

Synthesis and biological evaluation of 9-N-oxamyl sialosides as Siglec-7 ligands.

Prescher H, Gütgemann S, Frank M, Kuhfeldt E, Watzl C, Brossmer R. Prescher H, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5915-21. doi: 10.1016/j.bmc.2015.06.069. Epub 2015 Jul 7. Bioorg Med Chem. 2015. PMID: 26234906

3

Successful prediction of substrate-binding pocket in SLC17 transporter sialin.

Pietrancosta N, Anne C, Prescher H, Ruivo R, Sagné C, Debacker C, Bertrand HO, Brossmer R, Acher F, Gasnier B. Pietrancosta N, et al. Among authors: prescher h. J Biol Chem. 2012 Mar 30;287(14):11489-97. doi: 10.1074/jbc.M111.313056. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334707 Free PMC article.

4

Targeting of CD22-positive B-cell lymphoma cells by synthetic divalent sialic acid analogues.

Schweizer A, Wöhner M, Prescher H, Brossmer R, Nitschke L. Schweizer A, et al. Among authors: prescher h. Eur J Immunol. 2012 Oct;42(10):2792-802. doi: 10.1002/eji.201242574. Epub 2012 Aug 6. Eur J Immunol. 2012. PMID: 22777817 Free article.

5

Discovery of multifold modified sialosides as human CD22/Siglec-2 ligands with nanomolar activity on B-cells.

Prescher H, Schweizer A, Kuhfeldt E, Nitschke L, Brossmer R. Prescher H, et al. ACS Chem Biol. 2014 Jul 18;9(7):1444-50. doi: 10.1021/cb400952v. Epub 2014 May 7. ACS Chem Biol. 2014. PMID: 24807582

6

Design, Synthesis, and Biological Evaluation of Small, High-Affinity Siglec-7 Ligands: Toward Novel Inhibitors of Cancer Immune Evasion.

Prescher H, Frank M, Gütgemann S, Kuhfeldt E, Schweizer A, Nitschke L, Watzl C, Brossmer R. Prescher H, et al. J Med Chem. 2017 Feb 9;60(3):941-956. doi: 10.1021/acs.jmedchem.6b01111. Epub 2017 Jan 19. J Med Chem. 2017. PMID: 28103033

7

New Human CD22/Siglec-2 Ligands with a Triazole Glycoside.

Prescher H, Schweizer A, Kuhfeldt E, Nitschke L, Brossmer R. Prescher H, et al. Chembiochem. 2017 Jul 4;18(13):1216-1225. doi: 10.1002/cbic.201600707. Epub 2017 May 19. Chembiochem. 2017. PMID: 28374962

8

Targeting Human CD22/Siglec-2 with Dimeric Sialosides as Novel Oligosaccharide Mimetics.

Prescher H, Schweizer A, Frank M, Kuhfeldt E, Ring J, Nitschke L. Prescher H, et al. J Med Chem. 2022 Aug 11;65(15):10588-10610. doi: 10.1021/acs.jmedchem.2c00765. Epub 2022 Jul 26. J Med Chem. 2022. PMID: 35881556

9

Synthesis and Binding Mode Predictions of Novel Siglec-7 Ligands.

Frank M, Kuhfeldt E, Cramer J, Watzl C, Prescher H. Frank M, et al. Among authors: prescher h. J Med Chem. 2023 Oct 26;66(20):14315-14334. doi: 10.1021/acs.jmedchem.3c01349. Epub 2023 Oct 4. J Med Chem. 2023. PMID: 37793071

10

Avoiding Patient Abandonment: A Pathway to Ethical Resolution in Situations of Untenable Patient-Surgeon Relationships.

Prescher H, Gudex LM, Mauch JT, Vercler CJ. Prescher H, et al. Plast Reconstr Surg. 2024 Sep 10. doi: 10.1097/PRS.0000000000011735. Online ahead of print. Plast Reconstr Surg. 2024. PMID: 39252159

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