Jirkovská A - Search Results

1

Neonatal capsaicin administration impairs postnatal development of the cardiac chronotropy and inotropy in rats.

Kuncová J, Jirkovská A, Švíglerová J, Marková M, Meireles D, Čedíková M. Kuncová J, et al. Among authors: jirkovska a. Physiol Res. 2016 Dec 22;65(Suppl 5):S633-S642. doi: 10.33549/physiolres.933540. Physiol Res. 2016. PMID: 28006945 Free article.

2

Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury.

Jansová H, Macháček M, Wang Q, Hašková P, Jirkovská A, Potůčková E, Kielar F, Franz KJ, Simůnek T. Jansová H, et al. Among authors: jirkovska a. Free Radic Biol Med. 2014 Sep;74:210-21. doi: 10.1016/j.freeradbiomed.2014.06.019. Epub 2014 Jun 30. Free Radic Biol Med. 2014. PMID: 24992833 Free PMC article.

3

Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite.

Bures J, Jirkovska A, Sestak V, Jansova H, Karabanovich G, Roh J, Sterba M, Simunek T, Kovarikova P. Bures J, et al. Among authors: jirkovska a. Toxicology. 2017 Dec 1;392:1-10. doi: 10.1016/j.tox.2017.09.012. Epub 2017 Sep 21. Toxicology. 2017. PMID: 28941780

4

Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase IIβ Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity.

Kollárová-Brázdová P, Jirkovská A, Karabanovich G, Pokorná Z, Bavlovič Piskáčková H, Jirkovský E, Kubeš J, Lenčová-Popelová O, Mazurová Y, Adamcová M, Skalická V, Štěrbová-Kovaříková P, Roh J, Šimůnek T, Štěrba M. Kollárová-Brázdová P, et al. Among authors: jirkovska a. J Pharmacol Exp Ther. 2020 Jun;373(3):402-415. doi: 10.1124/jpet.119.264580. Epub 2020 Apr 6. J Pharmacol Exp Ther. 2020. PMID: 32253261

5

Proteomic investigation of embryonic rat heart-derived H9c2 cell line sheds new light on the molecular phenotype of the popular cell model.

Lenčo J, Lenčová-Popelová O, Link M, Jirkovská A, Tambor V, Potůčková E, Stulík J, Šimůnek T, Štěrba M. Lenčo J, et al. Among authors: jirkovska a. Exp Cell Res. 2015 Dec 10;339(2):174-86. doi: 10.1016/j.yexcr.2015.10.020. Epub 2015 Nov 5. Exp Cell Res. 2015. PMID: 26515555

6

Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products.

Jansová H, Bureš J, Macháček M, Hašková P, Jirkovská A, Roh J, Wang Q, Franz KJ, Kovaříková P, Šimůnek T. Jansová H, et al. Among authors: jirkovska a. Toxicology. 2016 Mar 28;350-352:15-24. doi: 10.1016/j.tox.2016.03.004. Epub 2016 Apr 1. Toxicology. 2016. PMID: 27046792 Free PMC article.

7

Detection and quantitation of iron in ferritin, transferrin and labile iron pool (LIP) in cardiomyocytes using ⁵⁵Fe and storage phosphorimaging.

Krijt M, Jirkovska A, Kabickova T, Melenovsky V, Petrak J, Vyoral D. Krijt M, et al. Among authors: jirkovska a. Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2895-2901. doi: 10.1016/j.bbagen.2018.09.005. Epub 2018 Sep 10. Biochim Biophys Acta Gen Subj. 2018. PMID: 30279145

8

UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study.

Reimerová P, Jirkovská A, Piskáčková HB, Karabanovich G, Roh J, Šimůnek T, Štěrbová-Kovaříková P. Reimerová P, et al. Among authors: jirkovska a. Sci Rep. 2019 Mar 14;9(1):4524. doi: 10.1038/s41598-019-40928-5. Sci Rep. 2019. PMID: 30872754 Free PMC article.

9

In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline.

Pokorna Z, Jirkovsky E, Hlavackova M, Jansova H, Jirkovska A, Lencova-Popelova O, Brazdova P, Kubes J, Sotakova-Kasparova D, Mazurova Y, Adamcova M, Vostatkova L, Holzerova K, Kolar F, Simunek T, Sterba M. Pokorna Z, et al. Among authors: jirkovska a. Clin Sci (Lond). 2019 Aug 27;133(16):1827-1844. doi: 10.1042/CS20190139. Print 2019 Aug 30. Clin Sci (Lond). 2019. PMID: 31409729

10

Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation.

Jirkovský E, Jirkovská A, Bavlovič-Piskáčková H, Skalická V, Pokorná Z, Karabanovich G, Kollárová-Brázdová P, Kubeš J, Lenčová-Popelová O, Mazurová Y, Adamcová M, Lyon AR, Roh J, Šimůnek T, Štěrbová-Kovaříková P, Štěrba M. Jirkovský E, et al. Among authors: jirkovska a. Circ Heart Fail. 2021 Nov;14(11):e008209. doi: 10.1161/CIRCHEARTFAILURE.120.008209. Epub 2021 Sep 23. Circ Heart Fail. 2021. PMID: 34551586

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