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Themis2 lowers the threshold for B cell activation during positive selection.
Cheng D, Deobagkar-Lele M, Zvezdova E, Choi S, Uehara S, Baup D, Bennett SC, Bull KR, Crockford TL, Ferry H, Warzecha C, Marcellin M, de Peredo AG, Lesourne R, Anzilotti C, Love PE, Cornall RJ. Cheng D, et al. Among authors: crockford tl. Nat Immunol. 2017 Feb;18(2):205-213. doi: 10.1038/ni.3642. Epub 2016 Dec 19. Nat Immunol. 2017. PMID: 27992403
Limited peripheral T cell anergy predisposes to retinal autoimmunity.
Lambe T, Leung JC, Ferry H, Bouriez-Jones T, Makinen K, Crockford TL, Jiang HR, Nickerson JM, Peltonen L, Forrester JV, Cornall RJ. Lambe T, et al. Among authors: crockford tl. J Immunol. 2007 Apr 1;178(7):4276-83. doi: 10.4049/jimmunol.178.7.4276. J Immunol. 2007. PMID: 17371984
DNA repair is limiting for haematopoietic stem cells during ageing.
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ. Nijnik A, et al. Among authors: crockford tl. Nature. 2007 Jun 7;447(7145):686-90. doi: 10.1038/nature05875. Nature. 2007. PMID: 17554302
29 results