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Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
Chung HK, Ryu D, Kim KS, Chang JY, Kim YK, Yi HS, Kang SG, Choi MJ, Lee SE, Jung SB, Ryu MJ, Kim SJ, Kweon GR, Kim H, Hwang JH, Lee CH, Lee SJ, Wall CE, Downes M, Evans RM, Auwerx J, Shong M. Chung HK, et al. Among authors: kim h, kim yk, kim sj, kim ks. J Cell Biol. 2017 Jan 2;216(1):149-165. doi: 10.1083/jcb.201607110. Epub 2016 Dec 16. J Cell Biol. 2017. PMID: 27986797 Free PMC article.
Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure.
Kim YK, Joung KH, Ryu MJ, Kim SJ, Kim H, Chung HK, Lee MH, Lee SE, Choi MJ, Chang JY, Hong HJ, Kim KS, Lee SH, Kweon GR, Kim H, Lee CH, Kim HJ, Shong M. Kim YK, et al. Among authors: kim h, kim hj, kim sj, kim ks. Diabetologia. 2015 Apr;58(4):771-80. doi: 10.1007/s00125-015-3506-y. Epub 2015 Feb 8. Diabetologia. 2015. PMID: 25660120
Regulation of systemic energy homeostasis by serotonin in adipose tissues.
Oh CM, Namkung J, Go Y, Shong KE, Kim K, Kim H, Park BY, Lee HW, Jeon YH, Song J, Shong M, Yadav VK, Karsenty G, Kajimura S, Lee IK, Park S, Kim H. Oh CM, et al. Among authors: kim h, kim k. Nat Commun. 2015 Apr 13;6:6794. doi: 10.1038/ncomms7794. Nat Commun. 2015. PMID: 25864946 Free PMC article.
Reduced oxidative capacity in macrophages results in systemic insulin resistance.
Jung SB, Choi MJ, Ryu D, Yi HS, Lee SE, Chang JY, Chung HK, Kim YK, Kang SG, Lee JH, Kim KS, Kim HJ, Kim CS, Lee CH, Williams RW, Kim H, Lee HK, Auwerx J, Shong M. Jung SB, et al. Among authors: kim cs, kim h, kim yk, kim hj, kim ks. Nat Commun. 2018 Apr 19;9(1):1551. doi: 10.1038/s41467-018-03998-z. Nat Commun. 2018. PMID: 29674655 Free PMC article.
PRMT1 Is Required for the Maintenance of Mature β-Cell Identity.
Kim H, Yoon BH, Oh CM, Lee J, Lee K, Song H, Kim E, Yi K, Kim MY, Kim H, Kim YK, Seo EH, Heo H, Kim HJ, Lee J, Suh JM, Koo SH, Seong JK, Kim S, Ju YS, Shong M, Kim M, Kim H. Kim H, et al. Among authors: kim e, kim yk, kim hj, kim s, kim m, kim my. Diabetes. 2020 Mar;69(3):355-368. doi: 10.2337/db19-0685. Epub 2019 Dec 17. Diabetes. 2020. PMID: 31848151
An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models.
Choi MJ, Jung SB, Lee SE, Kang SG, Lee JH, Ryu MJ, Chung HK, Chang JY, Kim YK, Hong HJ, Kim H, Kim HJ, Lee CH, Mardinoglu A, Yi HS, Shong M. Choi MJ, et al. Among authors: kim h, kim yk, kim hj. Diabetologia. 2020 Apr;63(4):837-852. doi: 10.1007/s00125-019-05082-7. Epub 2020 Jan 10. Diabetologia. 2020. PMID: 31925461
Lactation improves pancreatic β cell mass and function through serotonin production.
Moon JH, Kim H, Kim H, Park J, Choi W, Choi W, Hong HJ, Ro HJ, Jun S, Choi SH, Banerjee RR, Shong M, Cho NH, Kim SK, German MS, Jang HC, Kim H. Moon JH, et al. Among authors: kim h, kim sk. Sci Transl Med. 2020 Apr 29;12(541):eaay0455. doi: 10.1126/scitranslmed.aay0455. Sci Transl Med. 2020. PMID: 32350130 Free PMC article.
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