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Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.
Liao C, Ashley N, Diot A, Morten K, Phadwal K, Williams A, Fearnley I, Rosser L, Lowndes J, Fratter C, Ferguson DJ, Vay L, Quaghebeur G, Moroni I, Bianchi S, Lamperti C, Downes SM, Sitarz KS, Flannery PJ, Carver J, Dombi E, East D, Laura M, Reilly MM, Mortiboys H, Prevo R, Campanella M, Daniels MJ, Zeviani M, Yu-Wai-Man P, Simon AK, Votruba M, Poulton J. Liao C, et al. Among authors: east d. Neurology. 2017 Jan 10;88(2):131-142. doi: 10.1212/WNL.0000000000003491. Epub 2016 Dec 14. Neurology. 2017. PMID: 27974645 Free PMC article.
PMI: a ΔΨm independent pharmacological regulator of mitophagy.
East DA, Fagiani F, Crosby J, Georgakopoulos ND, Bertrand H, Schaap M, Fowkes A, Wells G, Campanella M. East DA, et al. Chem Biol. 2014 Nov 20;21(11):1585-96. doi: 10.1016/j.chembiol.2014.09.019. Chem Biol. 2014. PMID: 25455860 Free PMC article.
A role for TSPO in mitochondrial Ca2+ homeostasis and redox stress signaling.
Gatliff J, East DA, Singh A, Alvarez MS, Frison M, Matic I, Ferraina C, Sampson N, Turkheimer F, Campanella M. Gatliff J, et al. Among authors: east da. Cell Death Dis. 2017 Jun 22;8(6):e2896. doi: 10.1038/cddis.2017.186. Cell Death Dis. 2017. PMID: 28640253 Free PMC article.
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response.
Desai R, East DA, Hardy L, Faccenda D, Rigon M, Crosby J, Alvarez MS, Singh A, Mainenti M, Hussey LK, Bentham R, Szabadkai G, Zappulli V, Dhoot GK, Romano LE, Xia D, Coppens I, Hamacher-Brady A, Chapple JP, Abeti R, Fleck RA, Vizcay-Barrena G, Smith K, Campanella M. Desai R, et al. Among authors: east da. Sci Adv. 2020 Dec 18;6(51):eabc9955. doi: 10.1126/sciadv.abc9955. Print 2020 Dec. Sci Adv. 2020. PMID: 33355129 Free PMC article.
65 results