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Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.
Hughes DJ, Tiede C, Penswick N, Tang AA, Trinh CH, Mandal U, Zajac KZ, Gaule T, Howell G, Edwards TA, Duan J, Feyfant E, McPherson MJ, Tomlinson DC, Whitehouse A. Hughes DJ, et al. Among authors: feyfant e. Sci Signal. 2017 Nov 14;10(505):eaaj2005. doi: 10.1126/scisignal.aaj2005. Sci Signal. 2017. PMID: 29138295 Free PMC article.
Modeling mutations in protein structures.
Feyfant E, Sali A, Fiser A. Feyfant E, et al. Protein Sci. 2007 Sep;16(9):2030-41. doi: 10.1110/ps.072855507. Protein Sci. 2007. PMID: 17766392 Free PMC article.
Fragment-based drug design.
Feyfant E, Cross JB, Paris K, Tsao DH. Feyfant E, et al. Methods Mol Biol. 2011;685:241-52. doi: 10.1007/978-1-60761-931-4_12. Methods Mol Biol. 2011. PMID: 20981527
CONFIRM: connecting fragments found in receptor molecules.
Thompson DC, Denny RA, Nilakantan R, Humblet C, Joseph-McCarthy D, Feyfant E. Thompson DC, et al. Among authors: feyfant e. J Comput Aided Mol Des. 2008 Oct;22(10):761-72. doi: 10.1007/s10822-008-9221-8. Epub 2008 Jul 9. J Comput Aided Mol Des. 2008. PMID: 18612831
22 results