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Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval.
Ghouse J, Have CT, Weeke P, Bille Nielsen J, Ahlberg G, Balslev-Harder M, Appel EV, Skaaby T, Olesen SP, Grarup N, Linneberg A, Pedersen O, Haunsø S, Hastrup Svendsen J, Hansen T, Kanters JK, Salling Olesen M. Ghouse J, et al. Among authors: ahlberg g. Eur Heart J. 2015 Oct 1;36(37):2523-9. doi: 10.1093/eurheartj/ehv297. Epub 2015 Jul 9. Eur Heart J. 2015. PMID: 26159999
Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality.
Ghouse J, Have CT, Skov MW, Andreasen L, Ahlberg G, Nielsen JB, Skaaby T, Olesen SP, Grarup N, Linneberg A, Pedersen O, Vestergaard H, Haunsø S, Svendsen JH, Hansen T, Kanters JK, Olesen MS. Ghouse J, et al. Among authors: ahlberg g. Genet Med. 2017 May;19(5):521-528. doi: 10.1038/gim.2016.151. Epub 2016 Oct 6. Genet Med. 2017. PMID: 27711072 Free article.
Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants.
Gregers E, Ahlberg G, Christensen T, Jabbari J, Larsen KO, Herfelt CB, Henningsen KM, Andreasen L, Thiis JJ, Lund J, Holme S, Haunsø S, Bentzen BH, Schmitt N, Svendsen JH, Olesen MS. Gregers E, et al. Among authors: ahlberg g. Heart Rhythm. 2017 Oct;14(10):1531-1538. doi: 10.1016/j.hrthm.2017.05.027. Epub 2017 May 24. Heart Rhythm. 2017. PMID: 28549997
Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes.
Andreasen L, Ahlberg G, Tang C, Andreasen C, Hartmann JP, Tfelt-Hansen J, Behr ER, Pehrson S, Haunsø S, LuCamp, Weeke PE, Jespersen T, Olesen MS, Svendsen JH. Andreasen L, et al. Among authors: ahlberg g. Eur J Hum Genet. 2018 May;26(5):660-668. doi: 10.1038/s41431-017-0092-0. Epub 2018 Feb 2. Eur J Hum Genet. 2018. PMID: 29396561 Free PMC article.
Multi-ethnic genome-wide association study for atrial fibrillation.
Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarl… See abstract for full author list ➔ Roselli C, et al. Among authors: ahlberg g. Nat Genet. 2018 Jun 11;50(9):1225-1233. doi: 10.1038/s41588-018-0133-9. Nat Genet. 2018. PMID: 29892015 Free PMC article.
Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest.
Andreasen L, Ghouse J, Skov MW, Have CT, Ahlberg G, Rasmussen PV, Linneberg A, Pedersen O, Platonov PG, Haunsø S, Svendsen JH, Hansen T, Kanters JK, Olesen MS. Andreasen L, et al. Among authors: ahlberg g. Front Physiol. 2018 Jul 10;9:894. doi: 10.3389/fphys.2018.00894. eCollection 2018. Front Physiol. 2018. PMID: 30042696 Free PMC article.
94 results