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Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.
Kim SJ, Cheresh P, Jablonski RP, Morales-Nebreda L, Cheng Y, Hogan E, Yeldandi A, Chi M, Piseaux R, Ridge K, Michael Hart C, Chandel N, Scott Budinger GR, Kamp DW. Kim SJ, et al. Free Radic Biol Med. 2016 Dec;101:482-490. doi: 10.1016/j.freeradbiomed.2016.11.007. Epub 2016 Nov 11. Free Radic Biol Med. 2016. PMID: 27840320 Free PMC article.
Residual endotoxin induces primary graft dysfunction through ischemia/reperfusion-primed alveolar macrophages.
Akbarpour M, Lecuona E, Chiu SF, Wu Q, Querrey M, Fernandez R, Núñez-Santana FL, Sun H, Ravi S, Kurihara C, Walter JM, Joshi N, Ren Z, Roberts SC, Hauser A, Kreisel D, Li W, Chandel NS, Misharin AV, Mohanakumar T, Budinger GRS, Bharat A. Akbarpour M, et al. Among authors: chandel ns. J Clin Invest. 2020 Aug 3;130(8):4456-4469. doi: 10.1172/JCI135838. J Clin Invest. 2020. PMID: 32692317 Free PMC article.
Leptin resistance protects mice from hyperoxia-induced acute lung injury.
Bellmeyer A, Martino JM, Chandel NS, Scott Budinger GR, Dean DA, Mutlu GM. Bellmeyer A, et al. Among authors: chandel ns. Am J Respir Crit Care Med. 2007 Mar 15;175(6):587-94. doi: 10.1164/rccm.200603-312OC. Epub 2006 Dec 21. Am J Respir Crit Care Med. 2007. PMID: 17185651 Free PMC article.
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.
Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR. Mutlu GM, et al. Among authors: chandel ns. J Clin Invest. 2007 Oct;117(10):2952-61. doi: 10.1172/JCI30639. J Clin Invest. 2007. PMID: 17885684 Free PMC article.
Epithelial cell death is an important contributor to oxidant-mediated acute lung injury.
Budinger GR, Mutlu GM, Urich D, Soberanes S, Buccellato LJ, Hawkins K, Chiarella SE, Radigan KA, Eisenbart J, Agrawal H, Berkelhamer S, Hekimi S, Zhang J, Perlman H, Schumacker PT, Jain M, Chandel NS. Budinger GR, et al. Among authors: chandel ns. Am J Respir Crit Care Med. 2011 Apr 15;183(8):1043-54. doi: 10.1164/rccm.201002-0181OC. Epub 2010 Oct 19. Am J Respir Crit Care Med. 2011. PMID: 20959557 Free PMC article.
329 results