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Translational Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Inhibition Supports Dose-Range Selection of the Anti-PD-1 Antibody Pembrolizumab.
Lindauer A, Valiathan CR, Mehta K, Sriram V, de Greef R, Elassaiss-Schaap J, de Alwis DP. Lindauer A, et al. Among authors: valiathan cr. CPT Pharmacometrics Syst Pharmacol. 2017 Jan;6(1):11-20. doi: 10.1002/psp4.12130. Epub 2016 Nov 8. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 27863176 Free PMC article.
Atazanavir increases the plasma concentrations of 1200 mg raltegravir dose.
Krishna R, East L, Larson P, Valiathan C, Deschamps K, Luk JA, Bethel-Brown C, Manthos H, Brejda J, Gartner M. Krishna R, et al. Biopharm Drug Dispos. 2016 Dec;37(9):533-541. doi: 10.1002/bdd.2043. Epub 2016 Nov 4. Biopharm Drug Dispos. 2016. PMID: 27696440 Clinical Trial.