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52 results

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Page 1
Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).
Wolf D, Bukosza N, Engel D, Poggi M, Jehle F, Anto Michel N, Chen YC, Colberg C, Hoppe N, Dufner B, Boon L, Blankenbach H, Hilgendorf I, von Zur Muhlen C, Reinöhl J, Sommer B, Marchini T, Febbraio MA, Weber C, Bode C, Peter K, Lutgens E, Zirlik A. Wolf D, et al. Among authors: marchini t. Thromb Haemost. 2017 Jan 26;117(2):325-338. doi: 10.1160/TH16-07-0553. Epub 2016 Nov 17. Thromb Haemost. 2017. PMID: 27853810
Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.
Wolf D, Hohmann JD, Wiedemann A, Bledzka K, Blankenbach H, Marchini T, Gutte K, Zeschky K, Bassler N, Hoppe N, Rodriguez AO, Herr N, Hilgendorf I, Stachon P, Willecke F, Duerschmied D, von zur Muhlen C, Soloviev DA, Zhang L, Bode C, Plow EF, Libby P, Peter K, Zirlik A. Wolf D, et al. Among authors: marchini t. Circ Res. 2011 Nov 11;109(11):1269-79. doi: 10.1161/CIRCRESAHA.111.247684. Epub 2011 Oct 13. Circ Res. 2011. PMID: 21998326 Free PMC article.
Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice.
Willecke F, Tiwari S, Rupprecht B, Wolf D, Hergeth S, Hoppe N, Dufner B, Schulte L, Anto Michel N, Bukosza N, Marchini T, Jäckel M, Stachon P, Hilgendorf I, Zeschky K, Schleicher R, Langer HF, von Zur Muhlen C, Bode C, Peter K, Zirlik A. Willecke F, et al. Among authors: marchini t. Thromb Haemost. 2014 Aug;112(2):379-89. doi: 10.1160/TH13-08-0653. Epub 2014 Mar 20. Thromb Haemost. 2014. PMID: 24652469
P2Y6 deficiency limits vascular inflammation and atherosclerosis in mice.
Stachon P, Peikert A, Michel NA, Hergeth S, Marchini T, Wolf D, Dufner B, Hoppe N, Ayata CK, Grimm M, Cicko S, Schulte L, Reinöhl J, von zur Muhlen C, Bode C, Idzko M, Zirlik A. Stachon P, et al. Among authors: marchini t. Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2237-45. doi: 10.1161/ATVBAHA.114.303585. Epub 2014 Aug 7. Arterioscler Thromb Vasc Biol. 2014. PMID: 25104800
Acute exposure to air pollution particulate matter aggravates experimental myocardial infarction in mice by potentiating cytokine secretion from lung macrophages.
Marchini T, Wolf D, Michel NA, Mauler M, Dufner B, Hoppe N, Beckert J, Jäckel M, Magnani N, Duerschmied D, Tasat D, Alvarez S, Reinöhl J, von Zur Muhlen C, Idzko M, Bode C, Hilgendorf I, Evelson P, Zirlik A. Marchini T, et al. Basic Res Cardiol. 2016 Jul;111(4):44. doi: 10.1007/s00395-016-0562-5. Epub 2016 May 30. Basic Res Cardiol. 2016. PMID: 27240856 Free PMC article.
Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice.
Stachon P, Geis S, Peikert A, Heidenreich A, Michel NA, Ünal F, Hoppe N, Dufner B, Schulte L, Marchini T, Cicko S, Ayata K, Zech A, Wolf D, Hilgendorf I, Willecke F, Reinöhl J, von Zur Mühlen C, Bode C, Idzko M, Zirlik A. Stachon P, et al. Among authors: marchini t. Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1577-86. doi: 10.1161/ATVBAHA.115.307397. Epub 2016 Jun 23. Arterioscler Thromb Vasc Biol. 2016. PMID: 27339459
Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.
Anto Michel N, Colberg C, Buscher K, Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K, Marchini T, Willecke F, Stachon P, Hilgendorf I, Heidt T, von Zur Muhlen C, von Elverfeldt D, Pfeifer D, Schüle R, Kintscher U, Brachs S, Ley K, Bode C, Zirlik A, Wolf D. Anto Michel N, et al. Among authors: marchini t. Circ Res. 2018 Mar 2;122(5):693-700. doi: 10.1161/CIRCRESAHA.117.312055. Epub 2018 Jan 22. Circ Res. 2018. PMID: 29358227 Free PMC article.
A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.
Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, Zajonc DM, Hilgendorf I, Stachon P, Marchini T, Willecke F, Schell M, Sommer B, von Zur Muhlen C, Reinöhl J, Gerhardt T, Plow EF, Yakubenko V, Libby P, Bode C, Ley K, Peter K, Zirlik A. Wolf D, et al. Among authors: marchini t. Nat Commun. 2018 Feb 6;9(1):525. doi: 10.1038/s41467-018-02896-8. Nat Commun. 2018. PMID: 29410422 Free PMC article.
52 results