Packham G - Search Results

1

PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis.

Carter MJ, Cox KL, Blakemore SJ, Turaj AH, Oldham RJ, Dahal LN, Tannheimer S, Forconi F, Packham G, Cragg MS. Carter MJ, et al. Among authors: packham g. Leukemia. 2017 Jun;31(6):1423-1433. doi: 10.1038/leu.2016.333. Epub 2016 Nov 15. Leukemia. 2017. PMID: 27843137 Free PMC article.

2

Current strategies to target the anti-apoptotic Bcl-2 protein in cancer cells.

Osford SM, Dallman CL, Johnson PW, Ganesan A, Packham G. Osford SM, et al. Among authors: packham g. Curr Med Chem. 2004 Apr;11(8):1031-9. doi: 10.2174/0929867043455486. Curr Med Chem. 2004. PMID: 15083809 Review.

3

Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia.

Packham G, Stevenson FK. Packham G, et al. Immunology. 2005 Apr;114(4):441-9. doi: 10.1111/j.1365-2567.2005.02117.x. Immunology. 2005. PMID: 15804279 Free PMC article. Review.

4

Pharmacological inhibitors of NF-kappaB accelerate apoptosis in chronic lymphocytic leukaemia cells.

Pickering BM, de Mel S, Lee M, Howell M, Habens F, Dallman CL, Neville LA, Potter KN, Mann J, Mann DA, Johnson PW, Stevenson FK, Packham G. Pickering BM, et al. Among authors: packham g. Oncogene. 2007 Feb 22;26(8):1166-77. doi: 10.1038/sj.onc.1209897. Epub 2006 Aug 21. Oncogene. 2007. PMID: 16924235

5

Induction of cytosolic calcium flux by CD20 is dependent upon B Cell antigen receptor signaling.

Walshe CA, Beers SA, French RR, Chan CH, Johnson PW, Packham GK, Glennie MJ, Cragg MS. Walshe CA, et al. J Biol Chem. 2008 Jun 20;283(25):16971-84. doi: 10.1074/jbc.M708459200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18426802 Free article.

6

S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition.

Hayden A, Johnson PW, Packham G, Crabb SJ. Hayden A, et al. Among authors: packham g. Breast Cancer Res Treat. 2011 May;127(1):109-19. doi: 10.1007/s10549-010-0982-0. Epub 2010 Jun 17. Breast Cancer Res Treat. 2011. PMID: 20556507

7

Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia.

Paterson A, Mockridge CI, Adams JE, Krysov S, Potter KN, Duncombe AS, Cook SJ, Stevenson FK, Packham G. Paterson A, et al. Among authors: packham g. Blood. 2012 Feb 16;119(7):1726-36. doi: 10.1182/blood-2011-07-367417. Epub 2011 Dec 7. Blood. 2012. PMID: 22160382 Free article.

8

The IGHV1-69/IGHJ3 recombinations of unmutated CLL are distinct from those of normal B cells.

Forconi F, Potter KN, Sozzi E, Henderson I, Cencini E, Rossi D, Bomben R, Gattei V, Gaidano G, Packham G, Stevenson FK. Forconi F, et al. Among authors: packham g. Blood. 2012 Mar 1;119(9):2106-9. doi: 10.1182/blood-2011-08-375501. Epub 2012 Jan 10. Blood. 2012. PMID: 22234701 Free article.

9

Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function.

Coelho V, Krysov S, Steele A, Sanchez Hidalgo M, Johnson PW, Chana PS, Packham G, Stevenson FK, Forconi F. Coelho V, et al. Among authors: packham g. Blood. 2013 Oct 10;122(15):2664-72. doi: 10.1182/blood-2013-02-485425. Epub 2013 Aug 16. Blood. 2013. PMID: 23954894 Free article.

10

A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.

Horvilleur E, Sbarrato T, Hill K, Spriggs RV, Screen M, Goodrem PJ, Sawicka K, Chaplin LC, Touriol C, Packham G, Potter KN, Dirnhofer S, Tzankov A, Dyer MJ, Bushell M, MacFarlane M, Willis AE. Horvilleur E, et al. Among authors: packham g. Leukemia. 2014 May;28(5):1092-102. doi: 10.1038/leu.2013.295. Epub 2013 Oct 18. Leukemia. 2014. PMID: 24135829 Free PMC article.

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