Cragg MS - Search Results

1

PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis.

Carter MJ, Cox KL, Blakemore SJ, Turaj AH, Oldham RJ, Dahal LN, Tannheimer S, Forconi F, Packham G, Cragg MS. Carter MJ, et al. Among authors: cragg ms. Leukemia. 2017 Jun;31(6):1423-1433. doi: 10.1038/leu.2016.333. Epub 2016 Nov 15. Leukemia. 2017. PMID: 27843137 Free PMC article.

2

Induction of cytosolic calcium flux by CD20 is dependent upon B Cell antigen receptor signaling.

Walshe CA, Beers SA, French RR, Chan CH, Johnson PW, Packham GK, Glennie MJ, Cragg MS. Walshe CA, et al. Among authors: cragg ms. J Biol Chem. 2008 Jun 20;283(25):16971-84. doi: 10.1074/jbc.M708459200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18426802 Free article.

3

Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells.

Ivanov A, Beers SA, Walshe CA, Honeychurch J, Alduaij W, Cox KL, Potter KN, Murray S, Chan CH, Klymenko T, Erenpreisa J, Glennie MJ, Illidge TM, Cragg MS. Ivanov A, et al. Among authors: cragg ms. J Clin Invest. 2009 Aug;119(8):2143-59. doi: 10.1172/JCI37884. Epub 2009 Jul 20. J Clin Invest. 2009. PMID: 19620786 Free PMC article.

4

Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection.

Beers SA, French RR, Chan HT, Lim SH, Jarrett TC, Vidal RM, Wijayaweera SS, Dixon SV, Kim H, Cox KL, Kerr JP, Johnston DA, Johnson PW, Verbeek JS, Glennie MJ, Cragg MS. Beers SA, et al. Among authors: cragg ms. Blood. 2010 Jun 24;115(25):5191-201. doi: 10.1182/blood-2010-01-263533. Epub 2010 Mar 11. Blood. 2010. PMID: 20223920 Free article.

5

Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy.

Lim SH, Vaughan AT, Ashton-Key M, Williams EL, Dixon SV, Chan HT, Beers SA, French RR, Cox KL, Davies AJ, Potter KN, Mockridge CI, Oscier DG, Johnson PW, Cragg MS, Glennie MJ. Lim SH, et al. Among authors: cragg ms. Blood. 2011 Sep 1;118(9):2530-40. doi: 10.1182/blood-2011-01-330357. Epub 2011 Jul 18. Blood. 2011. PMID: 21768293 Free article.

6

Development and characterisation of monoclonal antibodies specific for the murine inhibitory FcγRIIB (CD32B).

Williams EL, Tutt AL, French RR, Chan HT, Lau B, Penfold CA, Mockridge CI, Roghanian A, Cox KL, Verbeek JS, Glennie MJ, Cragg MS. Williams EL, et al. Among authors: cragg ms. Eur J Immunol. 2012 Aug;42(8):2109-20. doi: 10.1002/eji.201142302. Epub 2012 Jul 4. Eur J Immunol. 2012. PMID: 22760702 Free article.

7

Transforming growth factor-β directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas.

Spender LC, Carter MJ, O'Brien DI, Clark LJ, Yu J, Michalak EM, Happo L, Cragg MS, Inman GJ. Spender LC, et al. Among authors: cragg ms. J Biol Chem. 2013 Feb 15;288(7):5198-209. doi: 10.1074/jbc.M112.410274. Epub 2012 Dec 14. J Biol Chem. 2013. PMID: 23243310 Free PMC article.

8

Immunotherapy targeting inhibitory Fcγ receptor IIB (CD32b) in the mouse is limited by monoclonal antibody consumption and receptor internalization.

Williams EL, Tutt AL, Beers SA, French RR, Chan CH, Cox KL, Roghanian A, Penfold CA, Butts CL, Boross P, Verbeek JS, Cragg MS, Glennie MJ. Williams EL, et al. Among authors: cragg ms. J Immunol. 2013 Oct 15;191(8):4130-40. doi: 10.4049/jimmunol.1301430. Epub 2013 Sep 11. J Immunol. 2013. PMID: 24026082

9

Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412.

Hussain K, Hargreaves CE, Roghanian A, Oldham RJ, Chan HT, Mockridge CI, Chowdhury F, Frendéus B, Harper KS, Strefford JC, Cragg MS, Glennie MJ, Williams AP, French RR. Hussain K, et al. Among authors: cragg ms. Blood. 2015 Jan 1;125(1):102-10. doi: 10.1182/blood-2014-08-593061. Epub 2014 Nov 13. Blood. 2015. PMID: 25395427 Free article.

10

Role of the pro-survival molecule Bfl-1 in melanoma.

Hind CK, Carter MJ, Harris CL, Chan HT, James S, Cragg MS. Hind CK, et al. Among authors: cragg ms. Int J Biochem Cell Biol. 2015 Feb;59:94-102. doi: 10.1016/j.biocel.2014.11.015. Epub 2014 Dec 6. Int J Biochem Cell Biol. 2015. PMID: 25486183

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