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The Central Nervous System and the Gut Microbiome.
Sharon G, Sampson TR, Geschwind DH, Mazmanian SK. Sharon G, et al. Among authors: geschwind dh. Cell. 2016 Nov 3;167(4):915-932. doi: 10.1016/j.cell.2016.10.027. Cell. 2016. PMID: 27814521 Free PMC article. Review.
Autism: many genes, common pathways?
Geschwind DH. Geschwind DH. Cell. 2008 Oct 31;135(3):391-5. doi: 10.1016/j.cell.2008.10.016. Cell. 2008. PMID: 18984147 Free PMC article.
A highly conserved program of neuronal microexons is misregulated in autistic brains.
Irimia M, Weatheritt RJ, Ellis JD, Parikshak NN, Gonatopoulos-Pournatzis T, Babor M, Quesnel-Vallières M, Tapial J, Raj B, O'Hanlon D, Barrios-Rodiles M, Sternberg MJ, Cordes SP, Roth FP, Wrana JL, Geschwind DH, Blencowe BJ. Irimia M, et al. Among authors: geschwind dh. Cell. 2014 Dec 18;159(7):1511-23. doi: 10.1016/j.cell.2014.11.035. Cell. 2014. PMID: 25525873 Free PMC article.
Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice.
Sharon G, Cruz NJ, Kang DW, Gandal MJ, Wang B, Kim YM, Zink EM, Casey CP, Taylor BC, Lane CJ, Bramer LM, Isern NG, Hoyt DW, Noecker C, Sweredoski MJ, Moradian A, Borenstein E, Jansson JK, Knight R, Metz TO, Lois C, Geschwind DH, Krajmalnik-Brown R, Mazmanian SK. Sharon G, et al. Among authors: geschwind dh. Cell. 2019 May 30;177(6):1600-1618.e17. doi: 10.1016/j.cell.2019.05.004. Cell. 2019. PMID: 31150625 Free PMC article.
A gut-derived metabolite alters brain activity and anxiety behaviour in mice.
Needham BD, Funabashi M, Adame MD, Wang Z, Boktor JC, Haney J, Wu WL, Rabut C, Ladinsky MS, Hwang SJ, Guo Y, Zhu Q, Griffiths JA, Knight R, Bjorkman PJ, Shapiro MG, Geschwind DH, Holschneider DP, Fischbach MA, Mazmanian SK. Needham BD, et al. Among authors: geschwind dh. Nature. 2022 Feb;602(7898):647-653. doi: 10.1038/s41586-022-04396-8. Epub 2022 Feb 14. Nature. 2022. PMID: 35165440 Free PMC article.
609 results