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Design and characterization of bivalent BET inhibitors.
Tanaka M, Roberts JM, Seo HS, Souza A, Paulk J, Scott TG, DeAngelo SL, Dhe-Paganon S, Bradner JE. Tanaka M, et al. Nat Chem Biol. 2016 Dec;12(12):1089-1096. doi: 10.1038/nchembio.2209. Epub 2016 Oct 24. Nat Chem Biol. 2016. PMID: 27775715 Free PMC article.
MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.
Kryukov GV, Wilson FH, Ruth JR, Paulk J, Tsherniak A, Marlow SE, Vazquez F, Weir BA, Fitzgerald ME, Tanaka M, Bielski CM, Scott JM, Dennis C, Cowley GS, Boehm JS, Root DE, Golub TR, Clish CB, Bradner JE, Hahn WC, Garraway LA. Kryukov GV, et al. Among authors: tanaka m. Science. 2016 Mar 11;351(6278):1214-8. doi: 10.1126/science.aad5214. Epub 2016 Feb 11. Science. 2016. PMID: 26912360 Free PMC article.
Compound 4f, a novel brain-penetrant reversible monoacylglycerol inhibitor, ameliorates neuroinflammation, neuronal cell loss, and cognitive impairment in mice with kainic acid-induced neurodegeneration.
Arimura N, Maeda C, Aoyama K, Yamaguchi N, Sugiura A, Takahashi Y, Maeda R, Ando T, Kamata M, Matsui H, Tanaka M. Arimura N, et al. Among authors: tanaka m. PLoS One. 2024 Nov 21;19(11):e0312090. doi: 10.1371/journal.pone.0312090. eCollection 2024. PLoS One. 2024. PMID: 39570850 Free PMC article.
Different impacts of granulocyte colony-stimulating factor administration on allogeneic hematopoietic cell transplant outcomes for adult acute myeloid leukemia according to graft type.
Konuma T, Kameda K, Morita K, Kondo T, Kimura F, Nakasone H, Ouchi F, Uchida N, Tanaka M, Nishida T, Fukuda T, Hasegawa Y, Sakata-Yanagimoto M, Onizuka M, Sawa M, Ota S, Asada N, Fujiwara SI, Yoshihara S, Ishimaru F, Yoshimitsu M, Kanda Y, Ohbiki M, Atsuta Y, Yanada M. Konuma T, et al. Among authors: tanaka m. Am J Hematol. 2024 Nov 20. doi: 10.1002/ajh.27521. Online ahead of print. Am J Hematol. 2024. PMID: 39564683
Reappraising the prognostic relevance of cytogenetic risk in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation.
Mizuno S, Hosoi H, Takami A, Kawata T, Doki N, Takeda W, Tanaka M, Nishida T, Uchida N, Hasegawa Y, Sawa M, Ota S, Onizuka M, Nakamae H, Asada N, Fukuda T, Yoshimitsu M, Kanda Y, Ohbiki M, Atsuta Y, Konuma T, Yanada M. Mizuno S, et al. Among authors: tanaka m. Ann Hematol. 2024 Nov 19. doi: 10.1007/s00277-024-06094-z. Online ahead of print. Ann Hematol. 2024. PMID: 39560740
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