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MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates.
Greene JM, Dash P, Roy S, McMurtrey C, Awad W, Reed JS, Hammond KB, Abdulhaqq S, Wu HL, Burwitz BJ, Roth BF, Morrow DW, Ford JC, Xu G, Bae JY, Crank H, Legasse AW, Dang TH, Greenaway HY, Kurniawan M, Gold MC, Harriff MJ, Lewinsohn DA, Park BS, Axthelm MK, Stanton JJ, Hansen SG, Picker LJ, Venturi V, Hildebrand W, Thomas PG, Lewinsohn DM, Adams EJ, Sacha JB. Greene JM, et al. Among authors: roy s. Mucosal Immunol. 2017 May;10(3):802-813. doi: 10.1038/mi.2016.91. Epub 2016 Oct 19. Mucosal Immunol. 2017. PMID: 27759023 Free PMC article.
TCR-pMHC bond conformation controls TCR ligand discrimination.
Sasmal DK, Feng W, Roy S, Leung P, He Y, Cai C, Cao G, Lian H, Qin J, Hui E, Schreiber H, Adams EJ, Huang J. Sasmal DK, et al. Among authors: roy s. Cell Mol Immunol. 2020 Mar;17(3):203-217. doi: 10.1038/s41423-019-0273-6. Epub 2019 Sep 17. Cell Mol Immunol. 2020. PMID: 31530899 Free PMC article.
MAIT cells are imprinted by the microbiota in early life and promote tissue repair.
Constantinides MG, Link VM, Tamoutounour S, Wong AC, Perez-Chaparro PJ, Han SJ, Chen YE, Li K, Farhat S, Weckel A, Krishnamurthy SR, Vujkovic-Cvijin I, Linehan JL, Bouladoux N, Merrill ED, Roy S, Cua DJ, Adams EJ, Bhandoola A, Scharschmidt TC, Aubé J, Fischbach MA, Belkaid Y. Constantinides MG, et al. Among authors: roy s. Science. 2019 Oct 25;366(6464):eaax6624. doi: 10.1126/science.aax6624. Science. 2019. PMID: 31649166 Free PMC article.
CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens.
Ly D, Kasmar AG, Cheng TY, de Jong A, Huang S, Roy S, Bhatt A, van Summeren RP, Altman JD, Jacobs WR Jr, Adams EJ, Minnaard AJ, Porcelli SA, Moody DB. Ly D, et al. Among authors: roy s. J Exp Med. 2013 Apr 8;210(4):729-41. doi: 10.1084/jem.20120624. Epub 2013 Mar 25. J Exp Med. 2013. PMID: 23530121 Free PMC article.
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