Radetzki S - Search Results

1

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma.

Du J, Neuenschwander M, Yu Y, Däbritz JH, Neuendorff NR, Schleich K, Bittner A, Milanovic M, Beuster G, Radetzki S, Specker E, Reimann M, Rosenbauer F, Mathas S, Lohneis P, Hummel M, Dörken B, von Kries JP, Lee S, Schmitt CA. Du J, et al. Among authors: radetzki s. Blood. 2017 Jan 5;129(1):71-81. doi: 10.1182/blood-2016-02-700773. Epub 2016 Oct 12. Blood. 2017. PMID: 27733358 Free article.

2

Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance.

Friedrich K, Wieder T, Von Haefen C, Radetzki S, Jänicke R, Schulze-Osthoff K, Dörken B, Daniel PT. Friedrich K, et al. Among authors: radetzki s. Oncogene. 2001 May 17;20(22):2749-60. doi: 10.1038/sj.onc.1204342. Oncogene. 2001. PMID: 11420687

3

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines.

Radetzki S, Köhne CH, von Haefen C, Gillissen B, Sturm I, Dörken B, Daniel PT. Radetzki S, et al. Oncogene. 2002 Jan 10;21(2):227-38. doi: 10.1038/sj.onc.1205010. Oncogene. 2002. PMID: 11803466

4

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.

Gillissen B, Essmann F, Graupner V, Stärck L, Radetzki S, Dörken B, Schulze-Osthoff K, Daniel PT. Gillissen B, et al. Among authors: radetzki s. EMBO J. 2003 Jul 15;22(14):3580-90. doi: 10.1093/emboj/cdg343. EMBO J. 2003. PMID: 12853473 Free PMC article.

5

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.

Sturm I, Stephan C, Gillissen B, Siebert R, Janz M, Radetzki S, Jung K, Loening S, Dörken B, Daniel PT. Sturm I, et al. Among authors: radetzki s. Cell Death Differ. 2006 Apr;13(4):619-27. doi: 10.1038/sj.cdd.4401782. Cell Death Differ. 2006. PMID: 16322756

6

Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells.

Wendt J, Radetzki S, von Haefen C, Hemmati PG, Güner D, Schulze-Osthoff K, Dörken B, Daniel PT. Wendt J, et al. Among authors: radetzki s. Oncogene. 2006 Feb 16;25(7):972-80. doi: 10.1038/sj.onc.1209031. Oncogene. 2006. PMID: 16331277

7

Silencing of APAF-1 in B-CLL results in poor prognosis in the case of concomitant p53 mutation.

Sturm I, Bosanquet AG, Radetzki S, Hummel M, Dörken B, Daniel PT. Sturm I, et al. Among authors: radetzki s. Int J Cancer. 2006 May 1;118(9):2329-36. doi: 10.1002/ijc.21535. Int J Cancer. 2006. PMID: 16331630

8

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.

Juneja M, Kobelt D, Walther W, Voss C, Smith J, Specker E, Neuenschwander M, Gohlke BO, Dahlmann M, Radetzki S, Preissner R, von Kries JP, Schlag PM, Stein U. Juneja M, et al. Among authors: radetzki s. PLoS Biol. 2017 Jun 1;15(6):e2000784. doi: 10.1371/journal.pbio.2000784. eCollection 2017 Jun. PLoS Biol. 2017. PMID: 28570591 Free PMC article.

9

Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations.

Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, Radetzki S, Vogt I, Hähn K, De Luca C, Cardoso C, Hamad S, Igual Gil C, Roy P, Albiges-Rizo C, Faurobert E, von Kries JP, Campillos M, Tournier-Lasserve E, Derry WB, Abdelilah-Seyfried S. Otten C, et al. Among authors: radetzki s. EMBO Mol Med. 2018 Oct;10(10):e9155. doi: 10.15252/emmm.201809155. EMBO Mol Med. 2018. PMID: 30181117 Free PMC article.

10

Revealing cytotoxic substructures in molecules using deep learning.

Webel HE, Kimber TB, Radetzki S, Neuenschwander M, Nazaré M, Volkamer A. Webel HE, et al. Among authors: radetzki s. J Comput Aided Mol Des. 2020 Jul;34(7):731-746. doi: 10.1007/s10822-020-00310-4. Epub 2020 Apr 16. J Comput Aided Mol Des. 2020. PMID: 32297073 Free PMC article.

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