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Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside.
Midtkandal RR, Redpath P, Trammell SA, Macdonald SJ, Brenner C, Migaud ME. Midtkandal RR, et al. Among authors: brenner c. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5204-7. doi: 10.1016/j.bmcl.2012.06.069. Epub 2012 Jun 28. Bioorg Med Chem Lett. 2012. PMID: 22795628 Free PMC article.
NNMT: A Bad Actor in Fat Makes Good in Liver.
Trammell SA, Brenner C. Trammell SA, et al. Among authors: brenner c. Cell Metab. 2015 Aug 4;22(2):200-1. doi: 10.1016/j.cmet.2015.07.017. Cell Metab. 2015. PMID: 26244929 Free PMC article.
Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice.
Trammell SA, Weidemann BJ, Chadda A, Yorek MS, Holmes A, Coppey LJ, Obrosov A, Kardon RH, Yorek MA, Brenner C. Trammell SA, et al. Among authors: brenner c. Sci Rep. 2016 May 27;6:26933. doi: 10.1038/srep26933. Sci Rep. 2016. PMID: 27230286 Free PMC article.
Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors.
Wilsbacher JL, Cheng M, Cheng D, Trammell SAJ, Shi Y, Guo J, Koeniger SL, Kovar PJ, He Y, Selvaraju S, Heyman HR, Sorensen BK, Clark RF, Hansen TM, Longenecker KL, Raich D, Korepanova AV, Cepa S, Towne DL, Abraham VC, Tang H, Richardson PL, McLoughlin SM, Badagnani I, Curtin ML, Michaelides MR, Maag D, Buchanan FG, Chiang GG, Gao W, Rosenberg SH, Brenner C, Tse C. Wilsbacher JL, et al. Among authors: brenner c. Mol Cancer Ther. 2017 Jul;16(7):1236-1245. doi: 10.1158/1535-7163.MCT-16-0819. Epub 2017 May 3. Mol Cancer Ther. 2017. PMID: 28468779
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.
Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. Fletcher RS, et al. Among authors: brenner c. Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752046 Free PMC article.
716 results