Lafarga V - Search Results

1

G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis.

Nogués L, Reglero C, Rivas V, Salcedo A, Lafarga V, Neves M, Ramos P, Mendiola M, Berjón A, Stamatakis K, Zhou XZ, Lu KP, Hardisson D, Mayor F Jr, Penela P. Nogués L, et al. Among authors: lafarga v. EBioMedicine. 2016 Nov;13:132-145. doi: 10.1016/j.ebiom.2016.09.030. Epub 2016 Oct 1. EBioMedicine. 2016. PMID: 27720394 Free PMC article.

2

The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets.

Penela P, Murga C, Ribas C, Lafarga V, Mayor F Jr. Penela P, et al. Among authors: lafarga v. Br J Pharmacol. 2010 Jun;160(4):821-32. doi: 10.1111/j.1476-5381.2010.00727.x. Br J Pharmacol. 2010. PMID: 20590581 Free PMC article. Review.

3

A novel GRK2/HDAC6 interaction modulates cell spreading and motility.

Lafarga V, Aymerich I, Tapia O, Mayor F Jr, Penela P. Lafarga V, et al. EMBO J. 2012 Feb 15;31(4):856-69. doi: 10.1038/emboj.2011.466. Epub 2011 Dec 23. EMBO J. 2012. PMID: 22193721 Free PMC article.

4

Roles of GRK2 in cell signaling beyond GPCR desensitization: GRK2-HDAC6 interaction modulates cell spreading and motility.

Penela P, Lafarga V, Tapia O, Rivas V, Nogués L, Lucas E, Vila-Bedmar R, Murga C, Mayor F Jr. Penela P, et al. Among authors: lafarga v. Sci Signal. 2012 May 15;5(224):pt3. doi: 10.1126/scisignal.2003098. Sci Signal. 2012. PMID: 22589388 Free article.

5

The interplay between G protein-coupled receptor kinase 2 (GRK2) and histone deacetylase 6 (HDAC6) at the crossroads of epithelial cell motility.

Lafarga V, Mayor F Jr, Penela P. Lafarga V, et al. Cell Adh Migr. 2012 Nov-Dec;6(6):495-501. doi: 10.4161/cam.21585. Epub 2012 Oct 17. Cell Adh Migr. 2012. PMID: 23076141 Free PMC article.

6

GRK2-Dependent HuR Phosphorylation Regulates HIF1α Activation under Hypoxia or Adrenergic Stress.

Reglero C, Lafarga V, Rivas V, Albitre Á, Ramos P, Berciano SR, Tapia O, Martínez-Chantar ML, Mayor F Jr, Penela P. Reglero C, et al. Among authors: lafarga v. Cancers (Basel). 2020 May 13;12(5):1216. doi: 10.3390/cancers12051216. Cancers (Basel). 2020. PMID: 32413989 Free PMC article.

7

GRK2-mediated AKT activation controls cell cycle progression and G2 checkpoint in a p53-dependent manner.

Rivas V, González-Muñoz T, Albitre Á, Lafarga V, Delgado-Arévalo C, Mayor F Jr, Penela P. Rivas V, et al. Among authors: lafarga v. Cell Death Discov. 2024 Aug 29;10(1):385. doi: 10.1038/s41420-024-02143-8. Cell Death Discov. 2024. PMID: 39198399 Free PMC article.

8

Efficacy of ATR inhibitors as single agents in Ewing sarcoma.

Nieto-Soler M, Morgado-Palacin I, Lafarga V, Lecona E, Murga M, Callen E, Azorin D, Alonso J, Lopez-Contreras AJ, Nussenzweig A, Fernandez-Capetillo O. Nieto-Soler M, et al. Among authors: lafarga v. Oncotarget. 2016 Sep 13;7(37):58759-58767. doi: 10.18632/oncotarget.11643. Oncotarget. 2016. PMID: 27577084 Free PMC article.

9

p18(Hamlet) mediates different p53-dependent responses to DNA-damage inducing agents.

Lafarga V, Cuadrado A, Nebreda AR. Lafarga V, et al. Cell Cycle. 2007 Oct 1;6(19):2319-22. doi: 10.4161/cc.6.19.4741. Epub 2007 Jul 12. Cell Cycle. 2007. PMID: 17700068

10

The SMN Tudor SIM-like domain is key to SmD1 and coilin interactions and to Cajal body biogenesis.

Tapia O, Lafarga V, Bengoechea R, Palanca A, Lafarga M, Berciano MT. Tapia O, et al. Among authors: lafarga m, lafarga v. J Cell Sci. 2014 Mar 1;127(Pt 5):939-46. doi: 10.1242/jcs.138537. Epub 2014 Jan 10. J Cell Sci. 2014. PMID: 24413165 Free article.

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