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Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.
Verfaillie A, Imrichova H, Atak ZK, Dewaele M, Rambow F, Hulselmans G, Christiaens V, Svetlichnyy D, Luciani F, Van den Mooter L, Claerhout S, Fiers M, Journe F, Ghanem GE, Herrmann C, Halder G, Marine JC, Aerts S. Verfaillie A, et al. Among authors: rambow f. Nat Commun. 2015 Apr 9;6:6683. doi: 10.1038/ncomms7683. Nat Commun. 2015. PMID: 25865119 Free PMC article.
Regulation of Melanoma Progression through the TCF4/miR-125b/NEDD9 Cascade.
Rambow F, Bechadergue A, Luciani F, Gros G, Domingues M, Bonaventure J, Meurice G, Marine JC, Larue L. Rambow F, et al. J Invest Dermatol. 2016 Jun;136(6):1229-1237. doi: 10.1016/j.jid.2016.02.803. Epub 2016 Mar 9. J Invest Dermatol. 2016. PMID: 26968260 Free article.
Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.
Riscal R, Schrepfer E, Arena G, Cissé MY, Bellvert F, Heuillet M, Rambow F, Bonneil E, Sabourdy F, Vincent C, Ait-Arsa I, Levade T, Thibaut P, Marine JC, Portais JC, Sarry JE, Le Cam L, Linares LK. Riscal R, et al. Among authors: rambow f. Mol Cell. 2016 Jun 16;62(6):890-902. doi: 10.1016/j.molcel.2016.04.033. Epub 2016 Jun 2. Mol Cell. 2016. PMID: 27264869 Free article.
Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma.
Olvedy M, Tisserand JC, Luciani F, Boeckx B, Wouters J, Lopez S, Rambow F, Aibar S, Thienpont B, Barra J, Köhler C, Radaelli E, Tartare-Deckert S, Aerts S, Dubreuil P, van den Oord JJ, Lambrechts D, De Sepulveda P, Marine JC. Olvedy M, et al. Among authors: rambow f. J Clin Invest. 2017 Jun 1;127(6):2310-2325. doi: 10.1172/JCI91291. Epub 2017 May 2. J Clin Invest. 2017. PMID: 28463229 Free PMC article.
A non-coding function of TYRP1 mRNA promotes melanoma growth.
Gilot D, Migault M, Bachelot L, Journé F, Rogiers A, Donnou-Fournet E, Mogha A, Mouchet N, Pinel-Marie ML, Mari B, Montier T, Corre S, Gautron A, Rambow F, El Hajj P, Ben Jouira R, Tartare-Deckert S, Marine JC, Felden B, Ghanem G, Galibert MD. Gilot D, et al. Among authors: rambow f. Nat Cell Biol. 2017 Nov;19(11):1348-1357. doi: 10.1038/ncb3623. Epub 2017 Oct 9. Nat Cell Biol. 2017. PMID: 28991221 Free article.
SCENIC: single-cell regulatory network inference and clustering.
Aibar S, González-Blas CB, Moerman T, Huynh-Thu VA, Imrichova H, Hulselmans G, Rambow F, Marine JC, Geurts P, Aerts J, van den Oord J, Atak ZK, Wouters J, Aerts S. Aibar S, et al. Among authors: rambow f. Nat Methods. 2017 Nov;14(11):1083-1086. doi: 10.1038/nmeth.4463. Epub 2017 Oct 9. Nat Methods. 2017. PMID: 28991892 Free PMC article.
Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.
Köhler C, Nittner D, Rambow F, Radaelli E, Stanchi F, Vandamme N, Baggiolini A, Sommer L, Berx G, van den Oord JJ, Gerhardt H, Blanpain C, Marine JC. Köhler C, et al. Among authors: rambow f. Cell Stem Cell. 2017 Nov 2;21(5):679-693.e6. doi: 10.1016/j.stem.2017.08.003. Epub 2017 Oct 12. Cell Stem Cell. 2017. PMID: 29033351 Free article.
Codon-specific translation reprogramming promotes resistance to targeted therapy.
Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, De Tullio P, Sin O, Shostak K, Schmitz S, Piepers J, Ghesquière B, Karim L, Charloteaux B, Jamart D, Florin A, Lambert C, Rorive A, Jerusalem G, Leucci E, Dewaele M, Vooijs M, Leidel SA, Georges M, Voz M, Peers B, Büttner R, Marine JC, Chariot A, Close P. Rapino F, et al. Among authors: rambow f. Nature. 2018 Jun;558(7711):605-609. doi: 10.1038/s41586-018-0243-7. Epub 2018 Jun 20. Nature. 2018. PMID: 29925953
Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.
Talebi A, Dehairs J, Rambow F, Rogiers A, Nittner D, Derua R, Vanderhoydonc F, Duarte JAG, Bosisio F, Van den Eynde K, Nys K, Pérez MV, Agostinis P, Waelkens E, Van den Oord J, Fendt SM, Marine JC, Swinnen JV. Talebi A, et al. Among authors: rambow f. Nat Commun. 2018 Jun 27;9(1):2500. doi: 10.1038/s41467-018-04664-0. Nat Commun. 2018. PMID: 29950559 Free PMC article.
66 results