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Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.
Harlow ML, Maloney N, Roland J, Guillen Navarro MJ, Easton MK, Kitchen-Goosen SM, Boguslawski EA, Madaj ZB, Johnson BK, Bowman MJ, D'Incalci M, Winn ME, Turner L, Hostetter G, Galmarini CM, Aviles PM, Grohar PJ. Harlow ML, et al. Among authors: galmarini cm. Cancer Res. 2016 Nov 15;76(22):6657-6668. doi: 10.1158/0008-5472.CAN-16-0568. Epub 2016 Oct 3. Cancer Res. 2016. PMID: 27697767 Free PMC article.
Unique features of trabectedin mechanism of action.
Larsen AK, Galmarini CM, D'Incalci M. Larsen AK, et al. Among authors: galmarini cm. Cancer Chemother Pharmacol. 2016 Apr;77(4):663-71. doi: 10.1007/s00280-015-2918-1. Epub 2015 Dec 14. Cancer Chemother Pharmacol. 2016. PMID: 26666647 Review.
Mechanism of action of trabectedin in desmoplastic small round cell tumor cells.
Uboldi S, Craparotta I, Colella G, Ronchetti E, Beltrame L, Vicario S, Marchini S, Panini N, Dagrada G, Bozzi F, Pilotti S, Galmarini CM, D'Incalci M, Gatta R. Uboldi S, et al. Among authors: galmarini cm. BMC Cancer. 2017 Feb 6;17(1):107. doi: 10.1186/s12885-017-3091-1. BMC Cancer. 2017. PMID: 28166781 Free PMC article.
Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models.
Belgiovine C, Bello E, Liguori M, Craparotta I, Mannarino L, Paracchini L, Beltrame L, Marchini S, Galmarini CM, Mantovani A, Frapolli R, Allavena P, D'Incalci M. Belgiovine C, et al. Among authors: galmarini cm. Br J Cancer. 2017 Aug 22;117(5):628-638. doi: 10.1038/bjc.2017.205. Epub 2017 Jul 6. Br J Cancer. 2017. PMID: 28683469 Free PMC article.
129 results