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Page 1
Progression of hypertension and kidney disease in aging fawn-hooded rats is mediated by enhanced influence of renin-angiotensin system and suppression of nitric oxide system and epoxyeicosanoids.
Doleželová Š, Jíchová Š, Husková Z, Vojtíšková A, Kujal P, Hošková L, Kautzner J, Sadowski J, Červenka L, Kopkan L. Doleželová Š, et al. Among authors: sadowski j. Clin Exp Hypertens. 2016;38(7):644-651. doi: 10.1080/10641963.2016.1182182. Epub 2016 Sep 26. Clin Exp Hypertens. 2016. PMID: 27669111
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
Kujal P, Chábová VČ, Vernerová Z, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Vaňourková Z, Husková Z, Opočenský M, Skaroupková P, Schejbalová S, Kramer HJ, Rakušan D, Malý J, Netuka I, Vaněčková I, Kopkan L, Cervenka L. Kujal P, et al. Among authors: sadowski j. Clin Exp Pharmacol Physiol. 2010 Dec;37(12):1159-69. doi: 10.1111/j.1440-1681.2010.05453.x. Clin Exp Pharmacol Physiol. 2010. PMID: 20880190
Addition of ET(A) receptor blockade increases renoprotection provided by renin-angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats.
Čertíková Chábová V, Vernerová Z, Kujal P, Husková Z, Škaroupková P, Tesař V, Kramer HJ, Kompanowska-Jezierska E, Walkowska A, Sadowski J, Červenka L, Vaněčková I. Čertíková Chábová V, et al. Among authors: sadowski j. Life Sci. 2014 Nov 24;118(2):297-305. doi: 10.1016/j.lfs.2013.12.018. Epub 2013 Dec 25. Life Sci. 2014. PMID: 24373834 Free article.
Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.
Sporková A, Jíchová S, Husková Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. Sporková A, et al. Among authors: sadowski j. Clin Exp Pharmacol Physiol. 2014 Dec;41(12):1003-13. doi: 10.1111/1440-1681.12310. Clin Exp Pharmacol Physiol. 2014. PMID: 25224811 Free PMC article.
Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
Alánová P, Husková Z, Kopkan L, Sporková A, Jíchová Š, Neckář J, Imig JD, Klevstig M, Kolář F, Rami Reddy N, Falck JR, Sadowski J, Nishiyama A, Kramer HJ, Melenovský V, Červenková L, Kujal P, Vernerová Z, Červenka L. Alánová P, et al. Among authors: sadowski j. Vascul Pharmacol. 2015 Oct;73:45-56. doi: 10.1016/j.vph.2015.08.013. Epub 2015 Aug 22. Vascul Pharmacol. 2015. PMID: 26304700
Intrarenal alterations of the angiotensin-converting enzyme type 2/angiotensin 1-7 complex of the renin-angiotensin system do not alter the course of malignant hypertension in Cyp1a1-Ren-2 transgenic rats.
Husková Z, Kopkan L, Červenková L, Doleželová Š, Vaňourková Z, Škaroupková P, Nishiyama A, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Červenka L. Husková Z, et al. Among authors: sadowski j. Clin Exp Pharmacol Physiol. 2016 Apr;43(4):438-49. doi: 10.1111/1440-1681.12553. Clin Exp Pharmacol Physiol. 2016. PMID: 26833491
Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Jíchová Š, Kopkan L, Husková Z, Doleželová Š, Neckář J, Kujal P, Vernerová Z, Kramer HJ, Sadowski J, Kompanowska-Jezierska E, Reddy RN, Falck JR, Imig JD, Červenka L. Jíchová Š, et al. Among authors: sadowski j. J Hypertens. 2016 Oct;34(10):2008-25. doi: 10.1097/HJH.0000000000001029. J Hypertens. 2016. PMID: 27428043 Free PMC article.
Renin-angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
Sedláková L, Čertíková Chábová V, Doleželová Š, Škaroupková P, Kopkan L, Husková Z, Červenková L, Kikerlová S, Vaněčková I, Sadowski J, Kompanowska-Jezierska E, Kujal P, Kramer HJ, Červenka L. Sedláková L, et al. Among authors: sadowski j. Clin Exp Hypertens. 2017;39(2):183-195. doi: 10.1080/10641963.2016.1235184. Epub 2017 Mar 1. Clin Exp Hypertens. 2017. PMID: 28287881
802 results