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Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, Dinh V, Kim SM, McDonald BD, Zurenski MA, Musch MW, Furtado GC, Lira SA, Baier G, Chang EB, Eren AM, Weber CR, Busque L, Godley LA, Verdú EF, Barreiro LB, Jabri B. Meisel M, et al. Among authors: chen l. Nature. 2018 May;557(7706):580-584. doi: 10.1038/s41586-018-0125-z. Epub 2018 May 16. Nature. 2018. PMID: 29769727 Free PMC article.
Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis.
Pandey SP, Bender MJ, McPherson AC, Phelps CM, Sanchez LM, Rana M, Hedden L, Sangani KA, Chen L, Shapira JH, Siller M, Goel C, Verdú EF, Jabri B, Chang A, Chandran UR, Mullett SJ, Wendell SG, Singhi AD, Tilstra JS, Pierre JF, Arteel GE, Hinterleitner R, Meisel M. Pandey SP, et al. Among authors: chen l. Cell Host Microbe. 2022 Jul 13;30(7):1003-1019.e10. doi: 10.1016/j.chom.2022.05.006. Epub 2022 Jun 2. Cell Host Microbe. 2022. PMID: 35658976 Free PMC article.
Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
Zhao Z, Chen L, Dawlaty MM, Pan F, Weeks O, Zhou Y, Cao Z, Shi H, Wang J, Lin L, Chen S, Yuan W, Qin Z, Ni H, Nimer SD, Yang FC, Jaenisch R, Jin P, Xu M. Zhao Z, et al. Among authors: chen l, chen s. Cell Rep. 2015 Nov 24;13(8):1692-704. doi: 10.1016/j.celrep.2015.10.037. Epub 2015 Nov 12. Cell Rep. 2015. PMID: 26586431 Free PMC article.
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Pan F, Wingo TS, Zhao Z, Gao R, Makishima H, Qu G, Lin L, Yu M, Ortega JR, Wang J, Nazha A, Chen L, Yao B, Liu C, Chen S, Weeks O, Ni H, Phillips BL, Huang S, Wang J, He C, Li GM, Radivoyevitch T, Aifantis I, Maciejewski JP, Yang FC, Jin P, Xu M. Pan F, et al. Among authors: chen l, chen s. Nat Commun. 2017 Apr 25;8:15102. doi: 10.1038/ncomms15102. Nat Commun. 2017. PMID: 28440315 Free PMC article.
Utility of five commonly used immunohistochemical markers TTF-1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases.
Gurda GT, Zhang L, Wang Y, Chen L, Geddes S, Cho WC, Askin F, Gabrielson E, Li QK. Gurda GT, et al. Among authors: chen l. Clin Transl Med. 2015 Apr 21;4:16. doi: 10.1186/s40169-015-0057-2. eCollection 2015. Clin Transl Med. 2015. PMID: 25977750 Free PMC article.
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