Mandinova A - Search Results

1

Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors.

Vafai SB, Mevers E, Higgins KW, Fomina Y, Zhang J, Mandinova A, Newman D, Shaw SY, Clardy J, Mootha VK. Vafai SB, et al. Among authors: mandinova a. PLoS One. 2016 Sep 13;11(9):e0162686. doi: 10.1371/journal.pone.0162686. eCollection 2016. PLoS One. 2016. PMID: 27622560 Free PMC article.

2

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.

Hiraki M, Hwang SY, Cao S, Ramadhar TR, Byun S, Yoon KW, Lee JH, Chu K, Gurkar AU, Kolev V, Zhang J, Namba T, Murphy ME, Newman DJ, Mandinova A, Clardy J, Lee SW. Hiraki M, et al. Among authors: mandinova a. Chem Biol. 2015 Sep 17;22(9):1206-16. doi: 10.1016/j.chembiol.2015.07.016. Epub 2015 Aug 27. Chem Biol. 2015. PMID: 26320861 Free PMC article.

3

Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling.

Hwang SY, Deng X, Byun S, Lee C, Lee SJ, Suh H, Zhang J, Kang Q, Zhang T, Westover KD, Mandinova A, Lee SW. Hwang SY, et al. Among authors: mandinova a. Cell Rep. 2016 Jun 28;16(1):28-36. doi: 10.1016/j.celrep.2016.05.071. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320923 Free PMC article.

4

GDC-0879, a BRAF^V600E Inhibitor, Protects Kidney Podocytes from Death.

Sieber J, Wieder N, Clark A, Reitberger M, Matan S, Schoenfelder J, Zhang J, Mandinova A, Bittker JA, Gutierrez J, Aygün O, Udeshi N, Carr S, Mundel P, Jehle AW, Greka A. Sieber J, et al. Among authors: mandinova a. Cell Chem Biol. 2018 Feb 15;25(2):175-184.e4. doi: 10.1016/j.chembiol.2017.11.006. Epub 2017 Dec 14. Cell Chem Biol. 2018. PMID: 29249695 Free PMC article.

5

High-throughput, high-content screening for novel pigmentation regulators using a keratinocyte/melanocyte co-culture system.

Lee JH, Chen H, Kolev V, Aull KH, Jung I, Wang J, Miyamoto S, Hosoi J, Mandinova A, Fisher DE. Lee JH, et al. Among authors: mandinova a. Exp Dermatol. 2014 Feb;23(2):125-9. doi: 10.1111/exd.12322. Exp Dermatol. 2014. PMID: 24438532 Free PMC article.

6

Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.

Kim HG, Tan L, Weisberg EL, Liu F, Canning P, Choi HG, Ezell SA, Wu H, Zhao Z, Wang J, Mandinova A, Griffin JD, Bullock AN, Liu Q, Lee SW, Gray NS. Kim HG, et al. Among authors: mandinova a. ACS Chem Biol. 2013 Oct 18;8(10):2145-50. doi: 10.1021/cb400430t. Epub 2013 Aug 13. ACS Chem Biol. 2013. PMID: 23899692 Free PMC article.

7

CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress.

Namba T, Tian F, Chu K, Hwang SY, Yoon KW, Byun S, Hiraki M, Mandinova A, Lee SW. Namba T, et al. Among authors: mandinova a. Cell Rep. 2013 Oct 31;5(2):331-9. doi: 10.1016/j.celrep.2013.09.020. Epub 2013 Oct 17. Cell Rep. 2013. PMID: 24139803 Free PMC article.

8

CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner.

Brown L, Ongusaha PP, Kim HG, Nuti S, Mandinova A, Lee JW, Khosravi-Far R, Aaronson SA, Lee SW. Brown L, et al. Among authors: mandinova a. EMBO J. 2007 Jul 25;26(14):3410-22. doi: 10.1038/sj.emboj.7601779. Epub 2007 Jun 28. EMBO J. 2007. PMID: 17599062 Free PMC article.

9

DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation.

Kim HG, Hwang SY, Aaronson SA, Mandinova A, Lee SW. Kim HG, et al. Among authors: mandinova a. J Biol Chem. 2011 May 20;286(20):17672-81. doi: 10.1074/jbc.M111.236612. Epub 2011 Mar 13. J Biol Chem. 2011. Retraction in: J Biol Chem. 2019 Dec 6;294(49):18950. doi: 10.1074/jbc.W119.011784 PMID: 21398698 Free PMC article. Retracted.

10

Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Among authors: mandinova a. Nature. 2011 Jul 13;475(7355):231-4. doi: 10.1038/nature10167. Nature. 2011. Retraction in: Nature. 2018 Sep;561(7723):420. doi: 10.1038/s41586-018-0284-y PMID: 21753854 Free PMC article. Retracted.

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