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An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice.
Rohm M, Schäfer M, Laurent V, Üstünel BE, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri EZ, Kemp BE, Steinberg GR, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S. Rohm M, et al. Among authors: zota a. Nat Med. 2016 Oct;22(10):1120-1130. doi: 10.1038/nm.4171. Epub 2016 Aug 29. Nat Med. 2016. PMID: 27571348
A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage.
Niopek K, Üstünel BE, Seitz S, Sakurai M, Zota A, Mattijssen F, Wang X, Sijmonsma T, Feuchter Y, Gail AM, Leuchs B, Niopek D, Staufer O, Brune M, Sticht C, Gretz N, Müller-Decker K, Hammes HP, Nawroth P, Fleming T, Conkright MD, Blüher M, Zeigerer A, Herzig S, Berriel Diaz M. Niopek K, et al. Among authors: zota a. Cell Rep. 2017 Aug 8;20(6):1422-1434. doi: 10.1016/j.celrep.2017.07.023. Cell Rep. 2017. PMID: 28793265 Free article.
Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes.
Okun JG, Rusu PM, Chan AY, Wu Y, Yap YW, Sharkie T, Schumacher J, Schmidt KV, Roberts-Thomson KM, Russell RD, Zota A, Hille S, Jungmann A, Maggi L, Lee Y, Blüher M, Herzig S, Keske MA, Heikenwalder M, Müller OJ, Rose AJ. Okun JG, et al. Among authors: zota a. Nat Metab. 2021 Mar;3(3):394-409. doi: 10.1038/s42255-021-00369-9. Epub 2021 Mar 18. Nat Metab. 2021. PMID: 33758419
microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis.
de Guia RM, Rose AJ, Sommerfeld A, Seibert O, Strzoda D, Zota A, Feuchter Y, Krones-Herzig A, Sijmonsma T, Kirilov M, Sticht C, Gretz N, Dallinga-Thie G, Diederichs S, Klöting N, Blüher M, Berriel Diaz M, Herzig S. de Guia RM, et al. Among authors: zota a. EMBO J. 2015 Feb 3;34(3):344-60. doi: 10.15252/embj.201490464. Epub 2014 Dec 15. EMBO J. 2015. PMID: 25510864 Free PMC article. Clinical Trial.
Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy.
Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, Wendler S, Männle D, Hinz U, Sticht C, Muciek M, Gretz N, Rose AJ, Greiner V, Hofmann TG, Bauer A, Hoheisel J, Berriel Diaz M, Gaida MM, Werner J, Schafmeier T, Strobel O, Herzig S. Stoy C, et al. Among authors: zota a. EMBO Mol Med. 2015 Aug;7(8):1048-62. doi: 10.15252/emmm.201404837. EMBO Mol Med. 2015. PMID: 26070712 Free PMC article.
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
Maida A, Zota A, Sjøberg KA, Schumacher J, Sijmonsma TP, Pfenninger A, Christensen MM, Gantert T, Fuhrmeister J, Rothermel U, Schmoll D, Heikenwälder M, Iovanna JL, Stemmer K, Kiens B, Herzig S, Rose AJ. Maida A, et al. Among authors: zota a. J Clin Invest. 2016 Sep 1;126(9):3263-78. doi: 10.1172/JCI85946. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548521 Free PMC article.
Molecular regulation of urea cycle function by the liver glucocorticoid receptor.
Okun JG, Conway S, Schmidt KV, Schumacher J, Wang X, de Guia R, Zota A, Klement J, Seibert O, Peters A, Maida A, Herzig S, Rose AJ. Okun JG, et al. Among authors: zota a. Mol Metab. 2015 Jul 30;4(10):732-40. doi: 10.1016/j.molmet.2015.07.006. eCollection 2015 Oct. Mol Metab. 2015. PMID: 26500844 Free PMC article.
99 results