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Disease Manifestation and Inflammatory Activity as Modulators of Th17/Treg Balance and RORC/FoxP3 Methylation in Systemic Sclerosis.
Almanzar G, Klein M, Schmalzing M, Hilligardt D, El Hajj N, Kneitz H, Wild V, Rosenwald A, Benoit S, Hamm H, Tony HP, Haaf T, Goebeler M, Prelog M. Almanzar G, et al. Among authors: klein m. Int Arch Allergy Immunol. 2016;171(2):141-154. doi: 10.1159/000450949. Epub 2016 Dec 1. Int Arch Allergy Immunol. 2016. PMID: 27902985 Free article.
T Cells Control Chemokine Secretion by Keratinocytes.
Rauschenberger T, Schmitt V, Azeem M, Klein-Hessling S, Murti K, Grän F, Goebeler M, Kerstan A, Klein M, Bopp T, Serfling E, Muhammad K. Rauschenberger T, et al. Among authors: klein m, klein hessling s. Front Immunol. 2019 Aug 9;10:1917. doi: 10.3389/fimmu.2019.01917. eCollection 2019. Front Immunol. 2019. PMID: 31447864 Free PMC article.
Memory CD4+ T cells lacking expression of CCR7 promote pro-inflammatory cytokine production in patients with diffuse cutaneous systemic sclerosis.
Almanzar G, Schmalzing M, Klein M, Hilligardt D, Morris P, Höfner K, Hajj NE, Kneitz H, Wild V, Rosenwald A, Benoit S, Hamm H, Tony HP, Haaf T, Goebeler M, Prelog M. Almanzar G, et al. Among authors: klein m. Eur J Dermatol. 2019 Oct 1;29(5):468-476. doi: 10.1684/ejd.2019.3645. Eur J Dermatol. 2019. PMID: 31789272
NFAT5 Controls the Integrity of Epidermis.
Muhammad K, Xavier D, Klein-Hessling S, Azeem M, Rauschenberger T, Murti K, Avots A, Goebeler M, Klein M, Bopp T, Sielaff M, Tenzer S, Möckel S, Aramburu J, López-Rodríguez C, Kerstan A, Serfling E. Muhammad K, et al. Among authors: klein m, klein hessling s. Front Immunol. 2021 Dec 9;12:780727. doi: 10.3389/fimmu.2021.780727. eCollection 2021. Front Immunol. 2021. PMID: 34956208 Free PMC article.
The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells.
Raczkowski F, Ritter J, Heesch K, Schumacher V, Guralnik A, Höcker L, Raifer H, Klein M, Bopp T, Harb H, Kesper DA, Pfefferle PI, Grusdat M, Lang PA, Mittrücker HW, Huber M. Raczkowski F, et al. Among authors: klein m. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):15019-24. doi: 10.1073/pnas.1309378110. Epub 2013 Aug 26. Proc Natl Acad Sci U S A. 2013. PMID: 23980171 Free PMC article.
NFATc1 controls the cytotoxicity of CD8+ T cells.
Klein-Hessling S, Muhammad K, Klein M, Pusch T, Rudolf R, Flöter J, Qureischi M, Beilhack A, Vaeth M, Kummerow C, Backes C, Schoppmeyer R, Hahn U, Hoth M, Bopp T, Berberich-Siebelt F, Patra A, Avots A, Müller N, Schulze A, Serfling E. Klein-Hessling S, et al. Among authors: klein m. Nat Commun. 2017 Sep 11;8(1):511. doi: 10.1038/s41467-017-00612-6. Nat Commun. 2017. PMID: 28894104 Free PMC article.
NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signaling.
Lacher SM, Thurm C, Distler U, Mohebiany AN, Israel N, Kitic M, Ebering A, Tang Y, Klein M, Wabnitz GH, Wanke F, Samstag Y, Bopp T, Kurschus FC, Simeoni L, Tenzer S, Waisman A. Lacher SM, et al. Among authors: klein m. J Autoimmun. 2018 Nov;94:110-121. doi: 10.1016/j.jaut.2018.07.017. Epub 2018 Jul 29. J Autoimmun. 2018. PMID: 30061013
IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis.
Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang Y, Klein M, Bittner S, Steffen F, Moos S, Marini F, Gloury R, Kurschus FC, Chao YY, Bertrams W, Sexl V, Schmeck B, Bonetti L, Grusdat M, Lohoff M, Zielinski CE, Zipp F, Kallies A, Brenner D, Berger M, Bopp T, Tackenberg B, Huber M. Lückel C, et al. Among authors: klein m. Nat Commun. 2019 Dec 16;10(1):5722. doi: 10.1038/s41467-019-13731-z. Nat Commun. 2019. PMID: 31844089 Free PMC article.
6,665 results