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The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection.
Delang L, Li C, Tas A, Quérat G, Albulescu IC, De Burghgraeve T, Guerrero NA, Gigante A, Piorkowski G, Decroly E, Jochmans D, Canard B, Snijder EJ, Pérez-Pérez MJ, van Hemert MJ, Coutard B, Leyssen P, Neyts J. Delang L, et al. Among authors: de burghgraeve t. Sci Rep. 2016 Aug 22;6:31819. doi: 10.1038/srep31819. Sci Rep. 2016. PMID: 27545976 Free PMC article.
Substituted imidazopyridines as potent inhibitors of HCV replication.
Vliegen I, Paeshuyse J, De Burghgraeve T, Lehman LS, Paulson M, Shih IH, Mabery E, Boddeker N, De Clercq E, Reiser H, Oare D, Lee WA, Zhong W, Bondy S, Pürstinger G, Neyts J. Vliegen I, et al. Among authors: de burghgraeve t, de clercq e. J Hepatol. 2009 May;50(5):999-1009. doi: 10.1016/j.jhep.2008.12.028. Epub 2009 Feb 26. J Hepatol. 2009. PMID: 19303654 Free PMC article.
A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro.
Kaptein SJ, De Burghgraeve T, Froeyen M, Pastorino B, Alen MM, Mondotte JA, Herdewijn P, Jacobs M, de Lamballerie X, Schols D, Gamarnik AV, Sztaricskai F, Neyts J. Kaptein SJ, et al. Among authors: de burghgraeve t, de lamballerie x. Antimicrob Agents Chemother. 2010 Dec;54(12):5269-80. doi: 10.1128/AAC.00686-10. Epub 2010 Sep 13. Antimicrob Agents Chemother. 2010. PMID: 20837762 Free PMC article.
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug.
Mastrangelo E, Pezzullo M, De Burghgraeve T, Kaptein S, Pastorino B, Dallmeier K, de Lamballerie X, Neyts J, Hanson AM, Frick DN, Bolognesi M, Milani M. Mastrangelo E, et al. Among authors: de burghgraeve t, de lamballerie x. J Antimicrob Chemother. 2012 Aug;67(8):1884-94. doi: 10.1093/jac/dks147. Epub 2012 Apr 25. J Antimicrob Chemother. 2012. PMID: 22535622 Free PMC article.
An analogue of the antibiotic teicoplanin prevents flavivirus entry in vitro.
De Burghgraeve T, Kaptein SJ, Ayala-Nunez NV, Mondotte JA, Pastorino B, Printsevskaya SS, de Lamballerie X, Jacobs M, Preobrazhenskaya M, Gamarnik AV, Smit JM, Neyts J. De Burghgraeve T, et al. Among authors: de lamballerie x. PLoS One. 2012;7(5):e37244. doi: 10.1371/journal.pone.0037244. Epub 2012 May 18. PLoS One. 2012. PMID: 22624001 Free PMC article.
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus.
Bassetto M, De Burghgraeve T, Delang L, Massarotti A, Coluccia A, Zonta N, Gatti V, Colombano G, Sorba G, Silvestri R, Tron GC, Neyts J, Leyssen P, Brancale A. Bassetto M, et al. Among authors: de burghgraeve t. Antiviral Res. 2013 Apr;98(1):12-8. doi: 10.1016/j.antiviral.2013.01.002. Epub 2013 Feb 1. Antiviral Res. 2013. PMID: 23380636 Free article.
3',5'Di-O-trityluridine inhibits in vitro flavivirus replication.
De Burghgraeve T, Selisko B, Kaptein S, Chatelain G, Leyssen P, Debing Y, Jacobs M, Van Aerschot A, Canard B, Neyts J. De Burghgraeve T, et al. Antiviral Res. 2013 May;98(2):242-7. doi: 10.1016/j.antiviral.2013.01.011. Epub 2013 Mar 5. Antiviral Res. 2013. PMID: 23470860
46 results