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Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis.
Karunakaran D, Geoffrion M, Wei L, Gan W, Richards L, Shangari P, DeKemp EM, Beanlands RA, Perisic L, Maegdefessel L, Hedin U, Sad S, Guo L, Kolodgie FD, Virmani R, Ruddy T, Rayner KJ. Karunakaran D, et al. Among authors: rayner kj. Sci Adv. 2016 Jul 22;2(7):e1600224. doi: 10.1126/sciadv.1600224. eCollection 2016 Jul. Sci Adv. 2016. PMID: 27532042 Free PMC article.
Serum heat shock protein 27 levels represent a potential therapeutic target for atherosclerosis: observations from a human cohort and treatment of female mice.
Seibert TA, Hibbert B, Chen YX, Rayner K, Simard T, Hu T, Cuerrier CM, Zhao X, de Belleroche J, Chow BJ, Hawken S, Wilson KR, O'Brien ER. Seibert TA, et al. J Am Coll Cardiol. 2013 Oct 15;62(16):1446-54. doi: 10.1016/j.jacc.2013.05.041. Epub 2013 Jun 10. J Am Coll Cardiol. 2013. PMID: 23764828 Free article.
MicroRNAs in cardiovascular health: from order to disorder.
Karunakaran D, Rayner KJ. Karunakaran D, et al. Among authors: rayner kj. Endocrinology. 2013 Nov;154(11):4000-9. doi: 10.1210/en.2013-1299. Epub 2013 Sep 5. Endocrinology. 2013. PMID: 24008347 Review.
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Ramkhelawon B, Hennessy EJ, Ménager M, Ray TD, Sheedy FJ, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner KJ, Moore KJ. Ramkhelawon B, et al. Among authors: rayner kj. Nat Med. 2014 Apr;20(4):377-84. doi: 10.1038/nm.3467. Epub 2014 Mar 2. Nat Med. 2014. PMID: 24584118 Free PMC article.
Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis.
Karunakaran D, Thrush AB, Nguyen MA, Richards L, Geoffrion M, Singaravelu R, Ramphos E, Shangari P, Ouimet M, Pezacki JP, Moore KJ, Perisic L, Maegdefessel L, Hedin U, Harper ME, Rayner KJ. Karunakaran D, et al. Among authors: rayner kj. Circ Res. 2015 Jul 17;117(3):266-78. doi: 10.1161/CIRCRESAHA.117.305624. Epub 2015 May 22. Circ Res. 2015. PMID: 26002865 Free PMC article.
IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis.
Chen HH, Keyhanian K, Zhou X, Vilmundarson RO, Almontashiri NA, Cruz SA, Pandey NR, Lerma Yap N, Ho T, Stewart CA, Huang H, Hari A, Geoffrion M, McPherson R, Rayner KJ, Stewart AF. Chen HH, et al. Among authors: rayner kj. Circ Res. 2015 Sep 25;117(8):671-83. doi: 10.1161/CIRCRESAHA.114.305777. Epub 2015 Jul 20. Circ Res. 2015. PMID: 26195219
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