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Page 1
Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension.
Shaw DE, Baig F, Bruce I, Chamoin S, Collingwood SP, Cross S, Dayal S, Drückes P, Furet P, Furminger V, Haggart D, Hussey M, Konstantinova I, Loren JC, Molteni V, Roberts S, Reilly J, Saunders AM, Stringer R, Sviridenko L, Thomas M, Thomson CG, Tomlins C, Wen B, Yeh V, Pearce AC. Shaw DE, et al. Among authors: konstantinova i. J Med Chem. 2016 Sep 8;59(17):7901-14. doi: 10.1021/acs.jmedchem.6b00703. Epub 2016 Aug 19. J Med Chem. 2016. PMID: 27502700
Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.
Ciuclan L, Hussey MJ, Burton V, Good R, Duggan N, Beach S, Jones P, Fox R, Clay I, Bonneau O, Konstantinova I, Pearce A, Rowlands DJ, Jarai G, Westwick J, MacLean MR, Thomas M. Ciuclan L, et al. Among authors: konstantinova i. Am J Respir Crit Care Med. 2013 Jan 1;187(1):78-89. doi: 10.1164/rccm.201206-1028OC. Epub 2012 Oct 18. Am J Respir Crit Care Med. 2013. PMID: 23087024
The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis.
Wettstein G, Luccarini JM, Poekes L, Faye P, Kupkowski F, Adarbes V, Defrêne E, Estivalet C, Gawronski X, Jantzen I, Philippot A, Tessier J, Tuyaa-Boustugue P, Oakley F, Mann DA, Leclercq I, Francque S, Konstantinova I, Broqua P, Junien JL. Wettstein G, et al. Among authors: konstantinova i. Hepatol Commun. 2017 Jun 19;1(6):524-537. doi: 10.1002/hep4.1057. eCollection 2017 Aug. Hepatol Commun. 2017. PMID: 29404476 Free PMC article.
The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis.
Derrett-Smith E, Clark KEN, Shiwen X, Abraham DJ, Hoyles RK, Lacombe O, Broqua P, Junien JL, Konstantinova I, Ong VH, Denton CP. Derrett-Smith E, et al. Among authors: konstantinova i. Arthritis Res Ther. 2021 Sep 6;23(1):234. doi: 10.1186/s13075-021-02592-x. Arthritis Res Ther. 2021. PMID: 34488870 Free PMC article.
Enzymatic Transglycosylation Features in Synthesis of 8-Aza-7-Deazapurine Fleximer Nucleosides by Recombinant E. coli PNP: Synthesis and Structure Determination of Minor Products.
Eletskaya BZ, Mironov AF, Fateev IV, Berzina MY, Antonov KV, Smirnova OS, Zatsepina AB, Arnautova AO, Abramchik YA, Paramonov AS, Kayushin AL, Khandazhinskaya AL, Matyugina ES, Kochetkov SN, Miroshnikov AI, Mikhailopulo IA, Esipov RS, Konstantinova ID. Eletskaya BZ, et al. Among authors: konstantinova id. Biomolecules. 2024 Jul 4;14(7):798. doi: 10.3390/biom14070798. Biomolecules. 2024. PMID: 39062512 Free PMC article.
Synthesis of Substituted 1,2,4-Triazole-3-Thione Nucleosides Using E. coli Purine Nucleoside Phosphorylase.
Fateev IV, Sasmakov SA, Abdurakhmanov JM, Ziyaev AA, Khasanov SS, Eshboev FB, Ashirov ON, Frolova VD, Eletskaya BZ, Smirnova OS, Berzina MY, Arnautova AO, Abramchik YA, Kostromina MA, Kayushin AL, Antonov KV, Paramonov AS, Andronova VL, Galegov GA, Esipov RS, Azimova SS, Miroshnikov AI, Konstantinova ID. Fateev IV, et al. Among authors: konstantinova id. Biomolecules. 2024 Jun 24;14(7):745. doi: 10.3390/biom14070745. Biomolecules. 2024. PMID: 39062460 Free PMC article.
New Biocides Based on N4-Alkylcytidines: Effects on Microorganisms and Application for the Protection of Cultural Heritage Objects of Painting.
Alexandrova LA, Oskolsky IA, Makarov DA, Jasko MV, Karpenko IL, Efremenkova OV, Vasilyeva BF, Avdanina DA, Ermolyuk AA, Benko EE, Kalinin SG, Kolganova TV, Berzina MY, Konstantinova ID, Chizhov AO, Kochetkov SN, Zhgun AA. Alexandrova LA, et al. Among authors: konstantinova id. Int J Mol Sci. 2024 Mar 6;25(5):3053. doi: 10.3390/ijms25053053. Int J Mol Sci. 2024. PMID: 38474298 Free PMC article.
New Flexible Analogues of 8-Aza-7-deazapurine Nucleosides as Potential Antibacterial Agents.
Khandazhinskaya A, Eletskaya B, Mironov A, Konstantinova I, Efremenkova O, Andreevskaya S, Smirnova T, Chernousova L, Kondrashova E, Chizhov A, Seley-Radtke K, Kochetkov S, Matyugina E. Khandazhinskaya A, et al. Among authors: konstantinova i. Int J Mol Sci. 2023 Oct 21;24(20):15421. doi: 10.3390/ijms242015421. Int J Mol Sci. 2023. PMID: 37895100 Free PMC article.
186 results