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Creation of "humanized" mice to study human immunity.
Pearson T, Greiner DL, Shultz LD. Pearson T, et al. Among authors: greiner dl. Curr Protoc Immunol. 2008 May;Chapter 15:15.21.1-15.21.21. doi: 10.1002/0471142735.im1521s81. Curr Protoc Immunol. 2008. PMID: 18491294 Free PMC article.
Humanized mouse models to study human diseases.
Brehm MA, Shultz LD, Greiner DL. Brehm MA, et al. Among authors: greiner dl. Curr Opin Endocrinol Diabetes Obes. 2010 Apr;17(2):120-5. doi: 10.1097/MED.0b013e328337282f. Curr Opin Endocrinol Diabetes Obes. 2010. PMID: 20150806 Free PMC article.
T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
Christianson SW, Greiner DL, Deluca D, Leif J, Phillips NE, Hayes SM, Hayashi S, Joliat MJ, Lyons BL, Shultz LD. Christianson SW, et al. Among authors: greiner dl. J Autoimmun. 2002 Mar;18(2):119-30. doi: 10.1006/jaut.2001.0571. J Autoimmun. 2002. PMID: 11908944
375 results