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Page 1
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
Pedigo CE, Ducasa GM, Leclercq F, Sloan A, Mitrofanova A, Hashmi T, Molina-David J, Ge M, Lassenius MI, Forsblom C, Lehto M, Groop PH, Kretzler M, Eddy S, Martini S, Reich H, Wahl P, Ghiggeri G, Faul C, Burke GW 3rd, Kretz O, Huber TB, Mendez AJ, Merscher S, Fornoni A. Pedigo CE, et al. Among authors: lassenius mi. J Clin Invest. 2016 Sep 1;126(9):3336-50. doi: 10.1172/JCI85939. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482889 Free PMC article.
Cyclodextrin protects podocytes in diabetic kidney disease.
Merscher-Gomez S, Guzman J, Pedigo CE, Lehto M, Aguillon-Prada R, Mendez A, Lassenius MI, Forsblom C, Yoo T, Villarreal R, Maiguel D, Johnson K, Goldberg R, Nair V, Randolph A, Kretzler M, Nelson RG, Burke GW 3rd, Groop PH, Fornoni A; FinnDiane Study Group. Merscher-Gomez S, et al. Among authors: lassenius mi. Diabetes. 2013 Nov;62(11):3817-27. doi: 10.2337/db13-0399. Epub 2013 Jul 8. Diabetes. 2013. PMID: 23835338 Free PMC article.
Cyclin-dependent kinase 2 protects podocytes from apoptosis.
Saurus P, Kuusela S, Dumont V, Lehtonen E, Fogarty CL, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Lehtonen S. Saurus P, et al. Among authors: lassenius mi. Sci Rep. 2016 Feb 15;6:21664. doi: 10.1038/srep21664. Sci Rep. 2016. PMID: 26876672 Free PMC article.
Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway.
Saurus P, Kuusela S, Lehtonen E, Hyvönen ME, Ristola M, Fogarty CL, Tienari J, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Holthöfer H, Lehtonen S. Saurus P, et al. Among authors: lassenius mi. Cell Death Dis. 2015 May 7;6(5):e1752. doi: 10.1038/cddis.2015.125. Cell Death Dis. 2015. PMID: 25950482 Free PMC article.
High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells.
Fogarty CL, Nieminen JK, Peräneva L, Lassenius MI, Ahola AJ, Taskinen MR, Jauhiainen M, Kirveskari J, Pussinen P, Hörkkö S, Mäkinen VP, Gordin D, Forsblom C, Groop PH, Vaarala O, Lehto M. Fogarty CL, et al. Among authors: lassenius mi. Acta Diabetol. 2015 Apr;52(2):315-22. doi: 10.1007/s00592-014-0641-8. Epub 2014 Sep 3. Acta Diabetol. 2015. PMID: 25182144
Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals.
Lassenius MI, Mäkinen VP, Fogarty CL, Peräneva L, Jauhiainen M, Pussinen PJ, Taskinen MR, Kirveskari J, Vaarala O, Nieminen JK, Hörkkö S, Kangas AJ, Soininen P, Ala-Korpela M, Gordin D, Ahola AJ, Forsblom C, Groop PH, Lehto M. Lassenius MI, et al. Nutr Metab (Lond). 2014 Jun 13;11:28. doi: 10.1186/1743-7075-11-28. eCollection 2014. Nutr Metab (Lond). 2014. PMID: 24959195 Free PMC article.
Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke.
Leskelä J, Toppila I, Härma MA, Palviainen T, Salminen A, Sandholm N, Pietiäinen M, Kopra E, Pais de Barros JP; FinnGen; Lassenius MI, Kumar A, Harjutsalo V, Roslund K, Forsblom C, Loukola A, Havulinna AS, Lagrost L, Salomaa V, Groop PH, Perola M, Kaprio J, Lehto M, Pussinen PJ. Leskelä J, et al. Among authors: lassenius mi. J Am Heart Assoc. 2021 Nov 2;10(21):e022482. doi: 10.1161/JAHA.121.022482. Epub 2021 Oct 20. J Am Heart Assoc. 2021. PMID: 34668383 Free PMC article.
34 results