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Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. Lee KS, et al. Among authors: wulff h. J Med Chem. 2014 Aug 28;57(16):7016-30. doi: 10.1021/jm500694p. Epub 2014 Aug 11. J Med Chem. 2014. PMID: 25079952 Free PMC article.
Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil.
Vasylieva N, Barnych B, Wan D, El-Sheikh EA, Nguyen HM, Wulff H, McMahen R, Strynar M, Gee SJ, Hammock BD. Vasylieva N, et al. Among authors: wulff h. Environ Int. 2017 Jun;103:91-98. doi: 10.1016/j.envint.2017.03.012. Epub 2017 Mar 23. Environ Int. 2017. PMID: 28343720 Free PMC article.
504 results