Robins-Browne RM - Search Results

1

Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target.

Soares da Costa TP, Desbois S, Dogovski C, Gorman MA, Ketaren NE, Paxman JJ, Siddiqui T, Zammit LM, Abbott BM, Robins-Browne RM, Parker MW, Jameson GB, Hall NE, Panjikar S, Perugini MA. Soares da Costa TP, et al. Structure. 2016 Aug 2;24(8):1282-1291. doi: 10.1016/j.str.2016.05.019. Epub 2016 Jul 14. Structure. 2016. PMID: 27427481 Free article.

2

From knock-out phenotype to three-dimensional structure of a promising antibiotic target from Streptococcus pneumoniae.

Dogovski C, Gorman MA, Ketaren NE, Praszkier J, Zammit LM, Mertens HD, Bryant G, Yang J, Griffin MD, Pearce FG, Gerrard JA, Jameson GB, Parker MW, Robins-Browne RM, Perugini MA. Dogovski C, et al. PLoS One. 2013 Dec 13;8(12):e83419. doi: 10.1371/journal.pone.0083419. eCollection 2013. PLoS One. 2013. PMID: 24349508 Free PMC article.

3

Disarming bacterial virulence through chemical inhibition of the DNA binding domain of an AraC-like transcriptional activator protein.

Yang J, Hocking DM, Cheng C, Dogovski C, Perugini MA, Holien JK, Parker MW, Hartland EL, Tauschek M, Robins-Browne RM. Yang J, et al. J Biol Chem. 2013 Oct 25;288(43):31115-26. doi: 10.1074/jbc.M113.503912. Epub 2013 Sep 9. J Biol Chem. 2013. PMID: 24019519 Free PMC article.

4

Bicarbonate-mediated stimulation of RegA, the global virulence regulator from Citrobacter rodentium.

Yang J, Dogovski C, Hocking D, Tauschek M, Perugini M, Robins-Browne RM. Yang J, et al. J Mol Biol. 2009 Dec 11;394(4):591-9. doi: 10.1016/j.jmb.2009.10.033. Epub 2009 Oct 21. J Mol Biol. 2009. PMID: 19853617

5

Control of Virulence Gene Expression by the Master Regulator, CfaD, in the Prototypical Enterotoxigenic Escherichia coli Strain, H10407.

Hodson C, Yang J, Hocking DM, Azzopardi K, Chen Q, Holien JK, Parker MW, Tauschek M, Robins-Browne RM. Hodson C, et al. Front Microbiol. 2017 Aug 11;8:1525. doi: 10.3389/fmicb.2017.01525. eCollection 2017. Front Microbiol. 2017. PMID: 28848532 Free PMC article.

6

Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein.

Yang J, Wilksch JJ, Tan JW, Hocking DM, Webb CT, Lithgow T, Robins-Browne RM, Strugnell RA. Yang J, et al. PLoS One. 2013 Nov 14;8(11):e79038. doi: 10.1371/journal.pone.0079038. eCollection 2013. PLoS One. 2013. PMID: 24244411 Free PMC article.

7

Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS.

Dunstan RA, Heinz E, Wijeyewickrema LC, Pike RN, Purcell AW, Evans TJ, Praszkier J, Robins-Browne RM, Strugnell RA, Korotkov KV, Lithgow T. Dunstan RA, et al. PLoS Pathog. 2013 Jan;9(1):e1003117. doi: 10.1371/journal.ppat.1003117. Epub 2013 Jan 10. PLoS Pathog. 2013. PMID: 23326233 Free PMC article.

8

Positive autoregulation of mrkHI by the cyclic di-GMP-dependent MrkH protein in the biofilm regulatory circuit of Klebsiella pneumoniae.

Tan JW, Wilksch JJ, Hocking DM, Wang N, Srikhanta YN, Tauschek M, Lithgow T, Robins-Browne RM, Yang J, Strugnell RA. Tan JW, et al. J Bacteriol. 2015 May;197(9):1659-67. doi: 10.1128/JB.02615-14. Epub 2015 Mar 2. J Bacteriol. 2015. PMID: 25733612 Free PMC article.

9

The type II secretion system and its ubiquitous lipoprotein substrate, SslE, are required for biofilm formation and virulence of enteropathogenic Escherichia coli.

Baldi DL, Higginson EE, Hocking DM, Praszkier J, Cavaliere R, James CE, Bennett-Wood V, Azzopardi KI, Turnbull L, Lithgow T, Robins-Browne RM, Whitchurch CB, Tauschek M. Baldi DL, et al. Infect Immun. 2012 Jun;80(6):2042-52. doi: 10.1128/IAI.06160-11. Epub 2012 Mar 26. Infect Immun. 2012. PMID: 22451516 Free PMC article.

10

The H-NS protein represses transcription of the eltAB operon, which encodes heat-labile enterotoxin in enterotoxigenic Escherichia coli, by binding to regions downstream of the promoter.

Yang J, Tauschek M, Strugnell R, Robins-Browne RM. Yang J, et al. Microbiology (Reading). 2005 Apr;151(Pt 4):1199-1208. doi: 10.1099/mic.0.27734-0. Microbiology (Reading). 2005. PMID: 15817787 Free article.

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