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Densely interconnected transcriptional circuits control cell states in human hematopoiesis.
Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, Dombkowski D, Evans JW, Liefeld T, Smutko JS, Chen J, Friedman N, Young RA, Golub TR, Regev A, Ebert BL. Novershtern N, et al. Among authors: regev a. Cell. 2011 Jan 21;144(2):296-309. doi: 10.1016/j.cell.2011.01.004. Cell. 2011. PMID: 21241896 Free PMC article.
Systematic discovery of TLR signaling components delineates viral-sensing circuits.
Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF, Gat-Viks I, Tonti E, DeGrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Andersen MS, Root DE, von Andrian U, Jones RB, Park H, Carr SA, Regev A, Amit I, Hacohen N. Chevrier N, et al. Among authors: regev a. Cell. 2011 Nov 11;147(4):853-67. doi: 10.1016/j.cell.2011.10.022. Cell. 2011. PMID: 22078882 Free PMC article.
Induction and molecular signature of pathogenic TH17 cells.
Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Lee Y, et al. Among authors: regev a. Nat Immunol. 2012 Oct;13(10):991-9. doi: 10.1038/ni.2416. Epub 2012 Sep 9. Nat Immunol. 2012. PMID: 22961052 Free PMC article.
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R. Sebastián C, et al. Among authors: regev a. Cell. 2012 Dec 7;151(6):1185-99. doi: 10.1016/j.cell.2012.10.047. Cell. 2012. PMID: 23217706 Free PMC article.
Dynamic regulatory network controlling TH17 cell differentiation.
Yosef N, Shalek AK, Gaublomme JT, Jin H, Lee Y, Awasthi A, Wu C, Karwacz K, Xiao S, Jorgolli M, Gennert D, Satija R, Shakya A, Lu DY, Trombetta JJ, Pillai MR, Ratcliffe PJ, Coleman ML, Bix M, Tantin D, Park H, Kuchroo VK, Regev A. Yosef N, et al. Among authors: regev a. Nature. 2013 Apr 25;496(7446):461-8. doi: 10.1038/nature11981. Epub 2013 Mar 6. Nature. 2013. PMID: 23467089 Free PMC article.
Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells.
Gazit R, Garrison BS, Rao TN, Shay T, Costello J, Ericson J, Kim F, Collins JJ, Regev A, Wagers AJ, Rossi DJ; Immunological Genome Project Consortium. Gazit R, et al. Among authors: regev a. Stem Cell Reports. 2013 Aug 15;1(3):266-80. doi: 10.1016/j.stemcr.2013.07.004. eCollection 2013. Stem Cell Reports. 2013. PMID: 24319662 Free PMC article.
Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.
Xiao S, Yosef N, Yang J, Wang Y, Zhou L, Zhu C, Wu C, Baloglu E, Schmidt D, Ramesh R, Lobera M, Sundrud MS, Tsai PY, Xiang Z, Wang J, Xu Y, Lin X, Kretschmer K, Rahl PB, Young RA, Zhong Z, Hafler DA, Regev A, Ghosh S, Marson A, Kuchroo VK. Xiao S, et al. Among authors: regev a. Immunity. 2014 Apr 17;40(4):477-89. doi: 10.1016/j.immuni.2014.04.004. Immunity. 2014. PMID: 24745332 Free PMC article.
615 results