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Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.
Pringle DR, Vasko VV, Yu L, Manchanda PK, Lee AA, Zhang X, Kirschner JM, Parlow AF, Saji M, Jarjoura D, Ringel MD, La Perle KM, Kirschner LS. Pringle DR, et al. Among authors: kirschner ls, kirschner jm. J Clin Endocrinol Metab. 2014 May;99(5):E804-12. doi: 10.1210/jc.2013-3101. Epub 2014 Feb 10. J Clin Endocrinol Metab. 2014. PMID: 24512487 Free PMC article.
BRAF activates and physically interacts with PAK to regulate cell motility.
McCarty SK, Saji M, Zhang X, Knippler CM, Kirschner LS, Fernandez S, Ringel MD. McCarty SK, et al. Among authors: kirschner ls. Endocr Relat Cancer. 2014;21(6):865-77. doi: 10.1530/ERC-14-0424. Epub 2014 Sep 16. Endocr Relat Cancer. 2014. PMID: 25228413 Free PMC article.
Automated MicroSPECT/MicroCT Image Analysis of the Mouse Thyroid Gland.
Cheng P, Hollingsworth B, Scarberry D, Shen DH, Powell K, Smart SC, Beech J, Sheng X, Kirschner LS, Menq CH, Jhiang SM. Cheng P, et al. Among authors: kirschner ls. Thyroid. 2017 Nov;27(11):1433-1440. doi: 10.1089/thy.2017.0264. Epub 2017 Oct 19. Thyroid. 2017. PMID: 28920557 Free PMC article.
Mouse models of thyroid cancer: A 2015 update.
Kirschner LS, Qamri Z, Kari S, Ashtekar A. Kirschner LS, et al. Mol Cell Endocrinol. 2016 Feb 5;421:18-27. doi: 10.1016/j.mce.2015.06.029. Epub 2015 Jun 27. Mol Cell Endocrinol. 2016. PMID: 26123589 Free PMC article. Review.
Inhibition of IGF-1R in adrenocortical carcinoma.
Kirschner LS. Kirschner LS. Lancet Oncol. 2015 Apr;16(4):356-7. doi: 10.1016/S1470-2045(15)70130-0. Epub 2015 Mar 18. Lancet Oncol. 2015. PMID: 25795411 No abstract available.
115 results