Desta Z - Search Results

1

Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele Carriers.

Abdelhady AM, Shugg T, Thong N, Lu JB, Kreutz Y, Jaynes HA, Robarge JD, Tisdale JE, Desta Z, Overholser BR. Abdelhady AM, et al. Among authors: desta z. J Cardiovasc Electrophysiol. 2016 Oct;27(10):1206-1213. doi: 10.1111/jce.13032. Epub 2016 Jul 25. J Cardiovasc Electrophysiol. 2016. PMID: 27333947 Free PMC article. Clinical Trial.

2

Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro.

Desta Z, Saussele T, Ward B, Blievernicht J, Li L, Klein K, Flockhart DA, Zanger UM. Desta Z, et al. Pharmacogenomics. 2007 Jun;8(6):547-58. doi: 10.2217/14622416.8.6.547. Pharmacogenomics. 2007. PMID: 17559344

3

Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients.

Borges S, Desta Z, Jin Y, Faouzi A, Robarge JD, Philips S, Nguyen A, Stearns V, Hayes D, Rae JM, Skaar TC, Flockhart DA, Li L. Borges S, et al. Among authors: desta z. J Clin Pharmacol. 2010 Apr;50(4):450-8. doi: 10.1177/0091270009359182. Epub 2010 Jan 15. J Clin Pharmacol. 2010. PMID: 20081063 Free PMC article.

4

Effects of the CYP2B6*6 allele on catalytic properties and inhibition of CYP2B6 in vitro: implication for the mechanism of reduced efavirenz metabolism and other CYP2B6 substrates in vivo.

Xu C, Ogburn ET, Guo Y, Desta Z. Xu C, et al. Among authors: desta z. Drug Metab Dispos. 2012 Apr;40(4):717-25. doi: 10.1124/dmd.111.042416. Epub 2012 Jan 9. Drug Metab Dispos. 2012. PMID: 22232427 Free PMC article.

5

Inhibition of platelet aggregation by prostaglandin E1 (PGE1) in diabetic patients during therapy with clopidogrel and aspirin.

Kreutz RP, Nystrom P, Kreutz Y, Miao J, Kovacs R, Desta Z, Flockhart DA, Jin Y. Kreutz RP, et al. Among authors: desta z. Platelets. 2013;24(2):145-50. doi: 10.3109/09537104.2012.661107. Epub 2012 Mar 2. Platelets. 2013. PMID: 22385219 Free PMC article.

6

Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response.

Kreutz RP, Nystrom P, Kreutz Y, Miao J, Desta Z, Breall JA, Li L, Chiang C, Kovacs R, Flockhart DA, Jin Y. Kreutz RP, et al. Among authors: desta z. Clin Pharmacol. 2012;4:13-20. doi: 10.2147/CPAA.S27822. Epub 2012 Feb 20. Clin Pharmacol. 2012. PMID: 22427735 Free PMC article.

7

CYP2B6 pharmacogenetics-based in vitro-in vivo extrapolation of efavirenz clearance by physiologically based pharmacokinetic modeling.

Xu C, Quinney SK, Guo Y, Hall SD, Li L, Desta Z. Xu C, et al. Among authors: desta z. Drug Metab Dispos. 2013 Dec;41(12):2004-11. doi: 10.1124/dmd.113.051755. Epub 2013 Jul 11. Drug Metab Dispos. 2013. PMID: 23846872 Free PMC article. Clinical Trial.

8

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response.

Kreutz RP, Owens J, Jin Y, Nystrom P, Desta Z, Kreutz Y, Breall JA, Li L, Chiang C, Kovacs RJ, Flockhart DA. Kreutz RP, et al. Among authors: desta z. Clin Pharmacol. 2013 Dec 9;5:185-92. doi: 10.2147/CPAA.S53151. eCollection 2013. Clin Pharmacol. 2013. PMID: 24353446 Free PMC article.

9

Substantial effect of efavirenz monotherapy on bilirubin levels in healthy volunteers.

Metzger IF, Quigg TC, Epstein N, Aregbe AO, Thong N, Callaghan JT, Flockhart DA, Nguyen AT, Stevens CK, Gupta SK, Desta Z. Metzger IF, et al. Among authors: desta z. Curr Ther Res Clin Exp. 2014 Sep 27;76:64-9. doi: 10.1016/j.curtheres.2014.05.002. eCollection 2014 Dec. Curr Ther Res Clin Exp. 2014. PMID: 25352936 Free PMC article.

10

In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases.

Cardoso Jde O, Oliveira RV, Lu JB, Desta Z. Cardoso Jde O, et al. Among authors: desta z. Drug Metab Dispos. 2015 Dec;43(12):1905-16. doi: 10.1124/dmd.115.065763. Drug Metab Dispos. 2015. PMID: 26374173 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

184 results

Search Page

Filters