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Cytokines: The Good, the Bad, and the Deadly.
Ramani T, Auletta CS, Weinstock D, Mounho-Zamora B, Ryan PC, Salcedo TW, Bannish G. Ramani T, et al. Among authors: ryan pc. Int J Toxicol. 2015 Jul-Aug;34(4):355-65. doi: 10.1177/1091581815584918. Epub 2015 May 26. Int J Toxicol. 2015. PMID: 26015504
Phase 1 Dose Escalation Study of MEDI-565, a Bispecific T-Cell Engager that Targets Human Carcinoembryonic Antigen, in Patients With Advanced Gastrointestinal Adenocarcinomas.
Pishvaian M, Morse MA, McDevitt J, Norton JD, Ren S, Robbie GJ, Ryan PC, Soukharev S, Bao H, Denlinger CS. Pishvaian M, et al. Among authors: ryan pc. Clin Colorectal Cancer. 2016 Dec;15(4):345-351. doi: 10.1016/j.clcc.2016.07.009. Epub 2016 Aug 4. Clin Colorectal Cancer. 2016. PMID: 27591895 Clinical Trial.
Effects of ICOS+ T cell depletion via afucosylated monoclonal antibody MEDI-570 on pregnant cynomolgus monkeys and the developing offspring.
Nicholson SM, Carlesso G, Cheng LI, Cook H, DaCosta K, Leininger J, McKeever K, Scott SW, Taylor D, Streicher K, Eck S, Reed M, Faggioni R, Herbst R, Dixit R, Ryan PC. Nicholson SM, et al. Among authors: ryan pc. Reprod Toxicol. 2017 Dec;74:116-133. doi: 10.1016/j.reprotox.2017.08.018. Epub 2017 Sep 13. Reprod Toxicol. 2017. PMID: 28916434
Fractionated Dosing Improves Preclinical Therapeutic Index of Pyrrolobenzodiazepine-Containing Antibody Drug Conjugates.
Hinrichs MJM, Ryan PM, Zheng B, Afif-Rider S, Yu XQ, Gunsior M, Zhong H, Harper J, Bezabeh B, Vashisht K, Rebelatto M, Reed M, Ryan PC, Breen S, Patel N, Chen C, Masterson L, Tiberghien A, Howard PW, Dimasi N, Dixit R. Hinrichs MJM, et al. Among authors: ryan pm, ryan pc. Clin Cancer Res. 2017 Oct 1;23(19):5858-5868. doi: 10.1158/1078-0432.CCR-17-0219. Epub 2017 Jun 19. Clin Cancer Res. 2017. PMID: 28630216
92 results