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Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF).
El Hayek L, Khalifeh M, Zibara V, Abi Assaad R, Emmanuel N, Karnib N, El-Ghandour R, Nasrallah P, Bilen M, Ibrahim P, Younes J, Abou Haidar E, Barmo N, Jabre V, Stephan JS, Sleiman SF. El Hayek L, et al. Among authors: sleiman sf. J Neurosci. 2019 Mar 27;39(13):2369-2382. doi: 10.1523/JNEUROSCI.1661-18.2019. Epub 2019 Jan 28. J Neurosci. 2019. PMID: 30692222 Free PMC article.
Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases.
Karnib N, El-Ghandour R, El Hayek L, Nasrallah P, Khalifeh M, Barmo N, Jabre V, Ibrahim P, Bilen M, Stephan JS, Holson EB, Ratan RR, Sleiman SF. Karnib N, et al. Among authors: sleiman sf. Neuropsychopharmacology. 2019 May;44(6):1152-1162. doi: 10.1038/s41386-019-0313-z. Epub 2019 Jan 8. Neuropsychopharmacology. 2019. PMID: 30647450 Free PMC article.
Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.
Aleyasin H, Karuppagounder SS, Kumar A, Sleiman S, Basso M, Ma T, Siddiq A, Chinta SJ, Brochier C, Langley B, Haskew-Layton R, Bane SL, Riggins GJ, Gazaryan I, Starkov AA, Andersen JK, Ratan RR. Aleyasin H, et al. Antioxid Redox Signal. 2015 Jan 10;22(2):121-34. doi: 10.1089/ars.2013.5595. Antioxid Redox Signal. 2015. PMID: 24766300 Free PMC article.
29 results